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Study of the anticancer activity of Budleina A

Grant number: 12/00260-0
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): March 01, 2012
Effective date (End): February 28, 2013
Field of knowledge:Biological Sciences - Immunology - Cellular Immunology
Principal Investigator:Ana Paula Campanelli
Grantee:Thalita Marcato Dalboni
Home Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil

Abstract

The anti-inflammatory activity of several medicinal plants from the family Asteraceae is due to the presence of sesquiterpene lactones.The anticancer activity of the Bludleina A will be investigated.Methods and Results: Tumor cells will be cultured with Budlein A for 24h and 48h and cells viability and Cytokines production analyzed By ELISA