Study of the anticancer activity of Budleina A

• Grant number: 12/00260-0
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: March 01, 2012
• End date: February 28, 2013
• Field of knowledge: Biological Sciences - Immunology - Cellular Immunology
• Principal Investigator: Ana Paula Campanelli
• Grantee: Thalita Marcato Dalboni
• Host Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil

Abstract

The anti-inflammatory activity of several medicinal plants from the family Asteraceae is due to the presence of sesquiterpene lactones. The anticancer activity of the bludleina A will be investigated. Methods and results: tumor cells will be cultured with budlein A for 24h and 48h and cells viability and Cytokines production analyzed By ELISA. (AU)