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Evaluation of the genotoxic potential of air pollution in workers exposed to vehicular emissions from Avenida Radial Leste, Sao Paulo.

Grant number: 12/06599-9
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): July 01, 2012
Effective date (End): July 31, 2014
Field of knowledge:Biological Sciences - Pharmacology - Toxicology
Principal Investigator:Regiani Carvalho de Oliveira
Grantee:Douglas Rene Rocha Silva
Home Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated scholarship(s):13/16062-5 - Evaluation of the genotoxic potential of air pollution in workers exposed to vehicular emissions from Avenida Radial Leste, São Paulo, BE.EP.IC

Abstract

In Sao Paulo vehicular traffic is the main emission source of air pollutants. Epidemiological studies indicate that current levels of air pollution in the city are related to increased mortality and morbidity. A characteristic observed in Sao Paulo, which is also observed in other urban centers, is the existence of the environmental racism. It is understood by this term that people with lower socioeconomic status tend to experience a greater gradient of environmental pollutant of lesser quality. The region where the Radial Leste Avenue passes has neighborhoods with different socioeconomic characteristics. This project aims to evaluate the influence of pollutants on the people who live or work along of the Avenue Radial Leste. For this, we will be use the micronuclei test in oral mucosa and in Tradescantia pallida.