Impact of neonatal risk and temperament in behavior of children born preterm in the pre-school age

• Grant number: 13/12509-5
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: September 01, 2013
• End date: September 30, 2017
• Field of knowledge: Humanities - Psychology - Psychological Treatment and Prevention
• Principal Investigator: Maria Beatriz Martins Linhares
• Grantee: Rafaela Guilherme Monte Cassiano
• Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated scholarship(s): 16/11533-8 - Prematurity and behavioral problems in two samples of toddlers from different cultures, BE.EP.DR

Abstract

Children born preterm and very low birth weight are more prone to having behavior problems and poor regulation in temperament compared to children born full term. It is important to advance the understanding of the impact of longitudinal neonatal risks experienced by preterm infants, associated with infant temperament, in their behavior, considering sample of high biological and social risk. This study aims to examine the predictive effect of neonatal and sociodemographic characteristics and temperament and behavior, evaluated during 18-36 months of age, the outcome of the behavior of children born preterm in preschool. The longitudinal study design includes three stages: neonatal, 18 to 36 months of age and pre-school (4-5 years). The sample will be composed of 100 children born preterm (<37 weeks gestational age) and very low birth weight (<1,500 grams). Data will be collected in a public teaching hospital. The following instruments will be applied: the Early Childhood Behavior Questionnaire (assessment of temperament), the Child Behavior Checklist 1 ½ -5 (behavior problems), Clinical Risk Index for Babies (CRIB) and the Neonatal Infant Stressor Scale (stress neonatal index). In addition, informations about the children´s health status will be collected in the medical records and the socioeconomic status of families will be caracterized. The data will be analyzed by statistical descriptive analysis and predictive analysis (linear multiple regression analysis). The predicted variable in this study will be the behavioral problems assessed at preschool age. The predictor variables are the following: neonatal variables (birth weight, gestational age, neonatal clinical risk index, stress index and length stay in the hospital), sociodemographic variables (maternal education, education of household head, and socioeconomic status) and variables of temperament and behavior, evaluated at 18-36 months of age. The data will be processed using SPSS, version 19.0 (Chicago, IL, USA) and the level of significance established in the study will be p d 0.05. The results will be organized and discussed according to the current literature of the area.

Scientific publications

(10)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

GASPARDO, CLAUDIA M.; CASSIANO, RAFAELA G. M.; GRACIOLI, SOFIA M. A.; FURINI, GUILHERME C. B.; LINHARES, MARIA BEATRIZ M.. Effects of Neonatal Pain and Temperament on Attention Problems in Toddlers Born Preterm. JOURNAL OF PEDIATRIC PSYCHOLOGY, v. 43, n. 3, SI, p. 342-351, APR 2018. (15/24117-0, 13/12509-5)

CASSIANO, RAFAELA G. M.; GASPARDO, CLAUDIA M.; MARTINS LINHARES, MARIA BEATRIZ. Temperament moderated by neonatal factors predicted behavioral problems in childhood: A prospective longitudinal study. EARLY HUMAN DEVELOPMENT, v. 135, n. SI, p. 37-43, AUG 2019. (13/12509-5)

CASSIANO, RAFAELA G. M.; PROVENZI, LIVIO; MARTINS LINHARES, MARIA BEATRIZ; GASPARDO, CLAUDIA M.; MONTIROSSO, ROSARIO. Does preterm birth affect child temperament? A meta-analytic study. INFANT BEHAVIOR & DEVELOPMENT, v. 58, FEB 2020. (16/11533-8, 13/12509-5)

MONTE CASSIANO, RAFAELA GUILHERME; PROVENZI, LIVIO; MARTINS LINHARES, MARIA BEATRIZ; GASPARDO, CLAUDIA MARIA; MONTIROSSO, ROSARIO. Maternal sociodemographic factors differentially affect the risk of behavioral problems in Brazilian and Italian preterm toddlers. INFANT BEHAVIOR & DEVELOPMENT, v. 50, p. 165-173, FEB 2018. (16/11533-8, 13/12509-5)

CASSIANO, RAFAELA G. M.; GASPARDO, CLAUDIA M.; LINHARES, MARIA BEATRIZ M.. PREMATURITY, NEONATAL HEALTH STATUS, AND LATER CHILD BEHAVIORAL/EMOTIONAL PROBLEMS: A SYSTEMATIC REVIEW. INFANT MENTAL HEALTH JOURNAL, v. 37, n. 3, p. 274-288, MAY-JUN 2016. (13/12509-5)

CASSIANO, RAFAELA G. M.; GASPARDO, CLAUDIA M.; LINHARES, MARIA B. M.. Neonatal Stress and Behavior Problems in Preschool Children Born Preterm. CLINICAL CHILD PSYCHOLOGY AND PSYCHIATRY, v. N/A, p. 12-pg., 2022-05-07. (13/12509-5)

MONTE CASSIANO, RAFAELA GUILHERME; GASPARDO, CLAUDIA MARIA; DE DEUS FACIROLI, RICARDO AUGUSTO; MARTINEZ, FRANCISCO EULOGIO; MARTINS LINHARES, MARIA BEATRIZ. Temperament and behavior in toddlers born preterm with related clinical problems. EARLY HUMAN DEVELOPMENT, v. 112, p. 1-8, SEP 2017. (13/12509-5)

MONTE CASSIANO, RAFAELA GUILHERME; GASPARDO, CLAUDIA MARIA; BUCKER FURINI, GUILHERME CORDARO; MARTINEZ, FRANCISCO EULOGIO; MARTINS LINHARES, MARIA. BEATRIZ. Impact of neonatal risk and temperament on behavioral problems in toddlers born preterm. EARLY HUMAN DEVELOPMENT, v. 103, p. 175-181, DEC 2016. (13/12509-5, 15/24117-0)

GASPARDO, CLAUDIA M.; CASSIANO, RAFAELA G. M.; GRACIOLI, SOFIA M. A.; FURINI, GUILHERME C. B.; LINHARES, MARIA BEATRIZ M.. Effects of Neonatal Pain and Temperament on Attention Problems in Toddlers Born Preterm. JOURNAL OF PEDIATRIC PSYCHOLOGY, v. 43, n. 3, p. 10-pg., 2018-04-01. (13/12509-5, 15/24117-0)

CASSIANO, RAFAELA G. M.; GASPARDO, CLAUDIA M.; MARTINS LINHARES, MARIA BEATRIZ. Temperament moderated by neonatal factors predicted behavioral problems in childhood: A prospective longitudinal study. EARLY HUMAN DEVELOPMENT, v. 135, p. 7-pg., 2019-08-01. (13/12509-5)