Development of polymeric biomaterials containing pharmacological activity

• Grant number: 14/00155-7
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: March 01, 2014
• End date: December 31, 2014
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Luiz Henrique Catalani
• Grantee: Caroline Guedes Monteiro
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 11/21442-6 - Synthetic and natural polymers applied to tissue engineering, AP.TEM

Abstract

This project aims to study polymers with pharmacological properties (polymer drugs) to produce scaffolds for cell growth. Thus, is intended to study the synthesis and characterization of a poly (anhydride-ester) derived from adipic and salicylic acid, as well as studies of production of blends with poly (L-lactide) (PLLA) and poly(L-lactide-co-glycolide) (PLGA), and the release of salicylic acid under simulated conditions of biodegradation.