Effects of pneumoperitoneum on ocular pressure in cats

• Grant number: 14/09250-2
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: August 01, 2014
• End date: November 30, 2015
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
• Principal Investigator: Cristiane dos Santos Honsho
• Grantee: Débora de Oliveira Garcia
• Host Institution: Pró-Reitoria Adjunta de Pesquisa e Pós-Graduação. Universidade de Franca (UNIFRAN). Franca , SP, Brazil

Abstract

Due to potential irreversible ophthalmic injuries caused by hyperinsuflation during abdominal laparoscopic procedures, this study aims to determine the possibility of such changes occur in cats in prospective study and randomized. For this, we used 10 cats of both sexes, clinically healthy, weighing 3.5 kg. The animals will be induced to anesthesia with isoflurane via induction's chamber, immediately be intubated and maintained with the same anesthetic agent. Intraocular pressure (IOP) will be measured by tonometry, moreover, will be assessed and recorded values of heart rate and respiratory rate, systolic, mean and diastolic blood pressure, rectal temperature, hydrogen potential in arterial blood (pHa) partial pressure of oxygen in arterial blood (PaO 2), partial pressure of carbon dioxide in arterial blood (PaCO2), arterial oxygen saturation (SaO2), bicarbonate ion (HCO 3), base deficit (DEB). Data will be collected at times: T0 - baseline; T15 - 15 minutes of general anesthesia with the animal in the supine position; (TIS) 5 min after abdominal insufflation, T30 and T60 understand 30 and 60 minutes after TIS, respectively. The results will be tested using the Shapiro-Wilk normality, when normally distributed will be employed analysis of variance (ANOVA) for repeated measures and Bonferroni's complementary analysis and variables with normal distribution are compared with the Wilcoxon test. The Pearson correlation test will be used to correlate the PaCO2, mean arterial pressure and positioning with the PO. The significance level is 5%.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE SOUZA, ARILTON TEODORO; GARCIA, DEBORA DE OLIVEIRA; NISHIMURA, LILIAN TOSHIKO; MAGALHAES, MARCOS LUCIO; MATTOS-JUNIOR, EWALDO; PAULINO-JUNIOR, DANIEL; JORGE, ADRIANA TORRECILHAS; HONSHO, CRISTIANE DOS SANTOS. EFFECTS OF PNEUMOPERITONEUM AND TRENDELENBURG POSITION ON INTRAOCULAR PRESSURE (IOP) IN ISOFLUORANE ANESTHETISED CATS. BIOSCIENCE JOURNAL, v. 35, n. 6, p. 1899-1906, NOV-DEC 2019. (14/09250-2)

DE SOUZA, ARILTON TEODORO; GARCIA, DEBORA DE OLIVEIRA; NISHIMURA, LILIAN TOSHIKO; MAGALHAES, MARCOS LUCIO; MATTOS-JUNIOR, EWALDO; PAULINO-JUNIOR, DANIEL; JORGE, ADRIANA TORRECILHAS; HONSHO, CRISTIANE DOS SANTOS. EFFECTS OF PNEUMOPERITONEUM AND TRENDELENBURG POSITION ON INTRAOCULAR PRESSURE (IOP) IN ISOFLUORANE ANESTHETISED CATS. BIOSCIENCE JOURNAL, v. 35, n. 6, p. 8-pg., 2019-11-01. (14/09250-2)