| Grant number: | 14/26262-4 |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| Start date: | April 01, 2015 |
| End date: | March 01, 2019 |
| Field of knowledge: | Biological Sciences - Genetics - Quantitative Genetics |
| Agreement: | Coordination of Improvement of Higher Education Personnel (CAPES) |
| Principal Investigator: | Gabriel Henrique Marroig Zambonato |
| Grantee: | Diogo Amaral Reboucas Melo |
| Host Institution: | Instituto de Biociências (IB). Universidade de São Paulo (USP). São Paulo , SP, Brazil |
| Associated research grant: | 11/14295-7 - Modularity and its evolutionary consequences, AP.TEM |
| Associated scholarship(s): | 15/21811-2 - Direct estimates of evolutionary parameters via QTL analysis, BE.EP.DR |
Abstract Quantitative genetics is the study of the natural variation and evolution of quantitative traits. The relation between traits isfundamental for the understanding of phenotypic diversification and the interaction of populations with their environment. The structure of relations between many continuously varying traits is expressed in their additive genetic covariance matrix. These genetic relations are in large part the result of pleiotropic and epistatic interactions between genes that influence many traits at the same time. While theoretical models provide us with a strong framework for understanding pleiotropy, there is a lack of empirical studies on the subject. In this project, we will investigate the evolution of pleiotropic relations on grow thrates, using artificially selected mice strains and quantitative traitloci detection. We will also use these experimental results to estimate parameters for individual based models of phenotypic evolution. (AU) | |
| News published in Agência FAPESP Newsletter about the scholarship: | |
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