The rehabilitation treatment with conventional complete dentures aims to restore chewing, phonetics and swallowing, as well as providing aesthetic and comfort. The success of this treatment should combine patient satisfaction with clinical and laboratory steps insightful and well executed, especially those that involve the impression procedures, registration of intermaxillary relations and choice of occlusal scheme. Currently, the most widespread occlusal scheme for complete dentures is the bilateral balanced occlusion (OBB), however, the canines guided occlusion (DC) represents a possible alternative on complete dentures fabrication. More randomized controlled trials to evaluate the effect of occlusal squemes regarding mastication are still needed. Objective: The aim of this study is to analyze the influence of occlusion guidance on masticatory performance and ability in complete denture wearers, by means of a cross-over study. Methodology: Edentulous individuals wearing conventional complete dentures will be invited for participation in this study (n= 40). After a period of adaptation to the new conventional complete dentures, will be divided into two study sequences where on alternate and sequential periods of 30 days each, will be assigned to two types of proposed protocols: Sequence 1 (bilateral balanced occlusion - OBB, followed by canines guidance - DC), and Sequence 2 (DC followed by OBB). Evaluations of masticatory performance and ability will be conducted by the sieves method and application specific questionnaire based on visual analogue scale (VAS), respectively, in different moments: 30 days after the adaptation period with the new dentures (Evaluation 1), and 60 days after the adaptation period with the new dentures (Evaluation 2). Masticatory performance will be evaluated by the sieves method using almonds, and expressed in percentage. The responses to the masticatory ability inventory will be measured from the VAS, and a mean value will be obatained for each group, expressed in millimeters. Data will be analyzed statistically with a significance level of 5%, by means of the IBM SPSS Statistics, (version 19.0), using appropriate test according to the adherence to normality.
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