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The impact of the control activities in the occurrence of visceral leishmaniasis in the municipalities of Araçatuba and Birigui - SP

Grant number: 15/18763-6
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): December 01, 2015
Effective date (End): November 30, 2016
Field of knowledge:Health Sciences - Collective Health
Principal Investigator:Francisco Chiaravalloti Neto
Grantee:Patricia Marques Moralejo Bermudi
Home Institution: Faculdade de Saúde Pública (FSP). Universidade de São Paulo (USP). São Paulo , SP, Brazil


Introduction: Visceral leishmaniasis (VL), currently considered one of the six priority endemic diseases in the world, has the control strategy: the diagnosis and treatment of human cases recorded, the elimination of the vector by applying residual insecticides and identification and removal of reservoirs, especially the canine. In Brazil, there are doubts in the effectiveness of control for reduced the incidence of the disease. Araçatuba and Birigui, two neighbors' municipalities of São Paulo, characterize this situation, since 2009 the incidence rates in Araçatuba falls while in Birigui the rates increased. Objectives: To describe the VL control activities in Birigui and Araçatuba during the period of 2006-2014; Assess the impact of the coverage of control activities in disease occurrence between 2007 and 2015, in both cities and compare the results between the two municipalities. Methods: The study will take place in urban areas of the cities. Information of VL control activities (canine survey and chemical control) will be grouped according to job sectors of SUCEN (Superintendent of Control and Endemic Diseases), and will be calculation the covers of activities during the period from 2006 to 2014. The indigenous cases of humans VL occurred between 2007 and 2015 will be georeference by home address and grouped according to the areas, with incidence rates. Will be produced thematic maps of the coverage of activities and control of VL and incidence rates, which allow visual comparison between these variables. To assess the degree of association between the VL occurrence and coverage of control activities will be used a spatial case-control design in a generalized additive model, allowing both to evaluate the spatial risk of the occurrence of VL, to check the degree of control measure influence in the occurrence of the disease and compare the results between the two municipalities.