Dosimetry of carbon dioxide laser for black tattoo removal

• Grant number: 15/24459-8
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: March 01, 2016
• End date: February 28, 2018
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Helio Plapler
• Grantee: Fabio D Arienzo
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil

Abstract

Objectives: to determine potency, energy and time parameters, which present better application to continuous Carbon Dioxide Laser for Tribal Black tattoo removal. Explanation: The applicant use of salabrasion for tattoo removal (practice dated from 543 a.C) proves the difficulty in fundamental advances at this domain. Recent studies from American Society for Dermatologic Surgery show that 5% of the global population has at least one tattoo and 10% of these people want to remove it, however, the lack of safe techniques exposes the population to risk treatments. By these data, researches aiming Laser's improvement at surgery's area are being done due to the new demand to safe and non-invasive technology. Method: 30 Wistar rats will undergo antisepsis and trichotomy of the dorsal region for quadrangular 2,2 cm x 2,2 cm Star rite Tribal Black tattooing with Black Line 210 machine and Black Line 07 MG needle. After 4 months in low/zero luminosity, 3 random groups (G1, G2 and G3) will be done, in such a way that all of them will undergo new trichotomy, Lidocaine 2% 40 mg/kg (intraperitoneal) without adrenalin anesthesia and Amoxicillin 150 mg/kg (oral) antibiotic therapy. Different dosimetry of continuous Carbon Dioxide Laser will be applied to the 3 groups respecting 4 weeks of interval until one group shows significant visual result or finishes 10 cycles of Laser application. In the end, an excision of 0,5 cm x 2,0 cm from the center of the studied region of the 3 groups will be done to morphological analysis and cell count, followed by statistical analysis. Results/Conclusion: It is expected that energy of 1,2J, potency of 10W and time of 0,12s as dosimetry of the Carbon Dioxide Laser show the best combination to tattoo removal with less skin injuries.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

D'ARIENZO, FABIO; COSTA DO BOMFIM, FERNANDO RUSSO; GONZALEZ SELLA, VALERIA REGINA; SIMOES, MANUEL DE JESUS; PLAPLER, HELIO. Dosimetry of a Carbon Dioxide Laser for Black Tattoo Removal in a Rat Model. Photomedicine and Laser Surgery, v. 36, n. 12, OCT 11 2018. (15/24459-8)