Surface modification of Ti-15Mo alloys to drugs release

• Grant number: 15/26273-9
• Support type: Scholarships abroad - Research Internship - Doctorate (Direct)
• Effective date (Start): July 23, 2016
• Effective date (End): May 22, 2017
• Field of knowledge: Interdisciplinary Subjects
• Principal Investigator: Ana Paula Rosifini Alves Claro
• Grantee: André Luiz Reis Rangel
• Supervisor abroad: Veronique Migonney
• Home Institution: Faculdade de Engenharia (FEG). Universidade Estadual Paulista (UNESP). Campus de Guaratinguetá. Guaratinguetá , SP, Brazil
• Local de pesquisa : Université Paris 13 - Nord, France
• Associated to the scholarship: 13/00317-4 - Surface modification of the Ti-15Mo alloy for drug delivery, BP.DD

Abstract

The aim of this project is to perform the drug immobilization over the surface of the Ti- 15Mo alloy after TiO2 nanotubes growth associated with polymeric coatings, in order to control the drugs release. The nanotubes will be obtained by anodic oxidation, the polymeric coating will be made by chemical and physical techniques. The biological response to the treatment will be studied by in vitro essays.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

RANGEL, ANDRE L. R.; FALENTIN-DAUDRE, CELINE; ALVES DA SILVA PIMENTEL, BRUNA NATALIA; VERGANI, CARLOS EDUARDO; MIGONNEY, VERONIQUE; ALVES CLARO, ANA P. R. Nanostructured titanium alloy surfaces for enhanced osteoblast response: A combination of morphology and chemistry. SURFACE & COATINGS TECHNOLOGY, v. 383, FEB 15 2020. Web of Science Citations: 0.