Repair process evaluation of rats' calvaria defects with bacterial cellulose and porcine collagen membrane: histometric, histological and Imuno-histochemical analysis

• Grant number: 15/23790-2
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: May 01, 2016
• End date: November 30, 2017
• Field of knowledge: Health Sciences - Dentistry - Oral and Maxillofacial Surgery
• Principal Investigator: Ana Paula Farnezi Bassi
• Grantee: Letícia de Freitas Mendes Brasil
• Host Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil

Abstract

Membranes that assist in guided bone regeneration process has been one of the research strands in bone repair. The use of these membranes has the purpose of creating a physical barrier in order to prevent fibrous tissue invasion in bone defects. Recently, research using cellulose has developed bioabsorbable membranes which can be used in various situations, particularly for burns and skin wounds, although there are still many questions regarding its behavior in bone tissue. Thus, the objective of this project is to evaluate through histological, immunohistochemistry and histometric analysis the auxiliary potential in guided bone regeneration of Green Tea membrane compared to porcine membrane (Bio-Guide® - Geistlich) and to a control group only with clot in the repair process of critical bone defects 8mm in calvaria of rats at 7,15, 30 and 60 days.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FARNEZI BASSI, ANA PAULA; BIZELLI, VINICIUS FERREIRA; DE MENDES BRASIL, LETICIA FREITAS; PEREIRA, JAREDE CARVALHO; AL-SHARANI, HESHAM MOHAMMED; CORREA MOMESSO, GUSTAVO ANTONIO; FAVERANI, LEONARDO P.; LUCAS, FLAVIA DE ALMEIDA. Is the Bacterial Cellulose Membrane Feasible for Osteopromotive Property?. MEMBRANES, v. 10, n. 9, p. 15-pg., 2020-09-01. (15/23790-2)