Development of electrochemical sensor modified with molecularly imprinted polymers (MIP) aiming cortisol quantification

• Grant number: 16/07416-6
• Support Opportunities: Scholarships in Brazil - Master
• Start date: January 01, 2017
• End date: February 28, 2018
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Agreement: Coordination of Improvement of Higher Education Personnel (CAPES)
• Principal Investigator: Thiago Regis Longo Cesar da Paixão
• Grantee: Letícia Francine Mendes
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Cortisol is a glucocorticoid hormone that is associated with several important physiologic processes, including inflammation, blood pressure, glucose metabolism, and fat metabolism. In addition, it is associated with acute stress; for example, emotional stress leads to cortisol release, which in turn facilitates the function of adrenaline and other catecholamines. Cortisol has been described as a potential index for stress, particularly for acute mental stressors. In this proposal we will develop a chemical sensor modified with molecurly imprinted polymers for detection of cortisol, a glucocorticoid hormone aiming at the fabrication of a wearable device to measure this hormone in real time in biological fluids. Molecularly imprinted polymers are materials with nanoscale features that imitate antibodies and other natural structures, like enzimes. (AU)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

MENDES, Letícia Francine. Development of electrochemical sensor modified with molecularly imprinted polymers (MIP) aiming cortisol quantification. 2018. Master's Dissertation - Universidade de São Paulo (USP). Conjunto das Químicas (IQ e FCF) (CQ/DBDCQ) São Paulo.