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Effects of photobiomodulation and Integra® dermal template supplemented with polyssacharide fraction of Lycium barbarum in an ex vivo wound healing model

Grant number: 16/24907-3
Support Opportunities:Scholarships abroad - Research Internship - Doctorate
Start date: March 01, 2017
End date: August 31, 2017
Field of knowledge:Health Sciences - Medicine
Principal Investigator:Márcia Regina Cominetti
Grantee:Lia Mara Grosso Neves
Supervisor: Ardeshir Bayat
Host Institution: Centro de Ciências Biológicas e da Saúde (CCBS). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil
Institution abroad: University of Manchester, England  
Associated to the scholarship:13/27021-8 - Effects of the fruit extract of Lycium barbarum L. and red laser in the prevention and treatment of photoaging in hairless mice SKH:hr-1, BP.DR

Abstract

The imperfect repair of chronic and acute ulcers still represents a therapeutic challenge in dermatology. The search for several modalities of non-invasive treatments has become the target of many researchers in order to find strategies that can favor the mechanisms of tissue repair, reducing the public expenditures dispensed with this problem. Phytotherapy has been used for decades in the treatment of wounds and its incorporation in human skin biocompatible materials has presented promising results, suggesting a new therapy for the cutaneous lesions treatment. Low-level laser is used as a physical and non-invasive method, which acts on the biomodulation of the tissue repair process, stimulating cell proliferation and angiogenesis. The association of different methods to promote a beneficial and supporting action in the healing process can result in an innovative therapy for tissue repair.

News published in Agência FAPESP Newsletter about the scholarship:
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VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
NEVES, LIA M. G.; PARIZOTTO, NIVALDO A.; COMINETTI, MARCIA R.; BAYAT, ARDESHIR. Photobiomodulation of a flowable matrix in a human skin ex vivo model demonstrates energy-based enhancement of engraftment integration and remodeling. Journal of Biophotonics, v. 11, n. 9, . (16/24907-3)