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Effect of the addition of trimetaphosphate and fluoride in a bleaching gel based on hydrogen peroxide at 35% on the hardness of the enamel submitted to the daily use of fluoridated dentifrice

Grant number: 16/26132-9
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): May 01, 2017
Effective date (End): November 30, 2017
Field of knowledge:Health Sciences - Dentistry - Pediatric Dentistry
Principal researcher:Alberto Carlos Botazzo Delbem
Grantee:Ronaldo Antônio Tolentino Prette Júnior
Home Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil


The possibility of minimizing enamel changes after tooth whitening would be of benefit to the patient. The aim of this study was to evaluate in vitro the addition of sodium trimetaphosphate (TMP) associated with 0.05% sodium fluoride, 35% hydrogen peroxide and the effect of daily use of fluoride dentifrice (1100 ppm F) during the experiment, on the hardness of the dental enamel. Bovine enamel blocks (4 mm x 4 mm, n = 40) will be selected through the initial surface hardness (SHI) and divided into four groups (n = 10), according to the treatments: 1) Hydrogen peroxide 35 % (PH); 2) PH + 0.05% NaF (PH/F); 3) PH + 0.05% NaF + 0.25% TMP (PH/F/TMP) and 4) HP Blue 35% (FGM - Dental Products: HP). The gels will be applied once, during 3 sessions of 40 minutes/session, every 7 days, totaling 21 days. Throughout the experiment the blocks will be treated with a slurry of dentifrice in the concentration of 1100 ppm F (1: 3), 2x/day. Between sessions of treatment and use of dentifrices the blocks will remain in artificial saliva that will be changed daily. Then the final surface hardness (SHF) and the percentage of surface hardness hardness loss (% SH) will be determined. Data will be submitted to ANOVA followed by Student-Newman-Keuls test (p < 0.05) if they present normal and homogeneous distribution. Otherwise, the Kruskal-Wallis analysis and the Student-Newman-Keuls test (p <0.05) will be used. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
PRETTE JUNIOR, RONALDO ANTONIO TOLENTINO; DANEION, MARCELLE; PESSAN, JULIANO PELIM; EMERENCIANO, NAYARA GONCALVES; CUNHA, ROBSON FREDERICO; SHINOHARA, MIRELA SANAE; BOTAZZO DELBEM, ALBERTO CARLOS. Effect of daily use of fluoridated dentifrice and bleaching gels containing calcium, fluoride, or trimetaphosphate on enamel hardness: an in vitro study. CLINICAL ORAL INVESTIGATIONS, v. 25, n. 3 JUN 2020. Web of Science Citations: 0.

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