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Study of the Guided Tissue Regeneration (GTR) through experimental analysis in temporo-mandibular joint's disc and NR-CaP occlusive membranes

Grant number: 17/03842-3
Support Opportunities:Scholarships abroad - Research Internship - Post-doctor
Start date: September 01, 2017
End date: August 31, 2018
Field of knowledge:Health Sciences - Dentistry - Dental Materials
Principal Investigator:Antônio Carlos Hernandes
Grantee:Rodney Marcelo do Nascimento
Supervisor: Rachid Rahouadj
Host Institution: Instituto de Física de São Carlos (IFSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
Institution abroad: Université de Lorraine (UL), France  
Associated to the scholarship:13/21970-8 - Development of biomaterial from the incorporation of calcium phosphates in latex structures to order application as controlled release device, BP.PD

Abstract

This project address a study of guided tissue regeneration through biomechanical characterizations of temporo-mandibular joint disc (TMJ) and Natural Rubber membranes. Samples will be investigated under a simulated biological environment as well as a living tissue response. Different experimental approaches such as inverse method and tensile-relaxation tests as well as theoretic modelling using a wide campaign of simulations regarding the paramount role of the tissue regeneration will be proposed. The main goals of the project are (i) to advance in understanding of the mechanisms responsible for tissue regeneration by a thorough analysis of the tissue behaviour, (ii) to provide a thorough analysis of the tissue behaviour predicting simulations and help dental surgeons, (iii) to provide a technique evaluation of natural rubber membranes aiming their optimization for clinical applications.

News published in Agência FAPESP Newsletter about the scholarship:
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Articles published in other media outlets ( ):
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VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DO NASCIMENTO, RODNEY MARCELO; SARIG, UDI; DO CRUZ, NILSON CRISTINO; DE CARVALHO, VANESSA RAFAELA; EYSSARTIER, CAMILLE; SIAD, LARBI; GANGHOFFER, JEAN-FRANCOIS; HERNANDES, ANTONIO CARLOS; RAHOUADJ, RACHID. Optimized-Surface Wettability: A New Experimental 3D Modeling Approach Predicting Favorable Biomaterial-Cell Interactions. ADVANCED THEORY AND SIMULATIONS, v. 2, n. 7, . (17/03842-3, 13/21970-8)
DO NASCIMENTO, RODNEY MARCELO; SCHMITT, JEAN-FRANCOIS; SARIG, UDI; FIGUEIREDO SOARES RODRIGUES, JOAO ELIAS; PECHARROMAN, CARLOS; RAMOS, ANA PAULA; CIANCAGLINI, PIETRO; FAITA, FABRICIO LUIZ; RAHOUADJ, RACHID; HERNANDES, ANTONIO CARLOS; et al. Surface Wettability of a Natural Rubber Composite under Stretching: A Model to Predict Cell Survival. Langmuir, v. 37, n. 15, p. 4639-4646, . (13/21970-8, 17/03842-3)
DO NASCIMENTO, RODNEY MARCELO; BALDIT, ADRIEN; KOKANYAN, NINEL; TAPPERT, LARA KRISTIN; LIPINSKI, PAUL; HERNANDES, ANTONIO CARLOS; RAHOUADJ, RACHID. Mechanical-chemical coupling in Temporomandibular Joint disc. MATERIALIA, v. 9, . (17/03842-3, 13/21970-8)