| Grant number: | 17/18487-4 |
| Support Opportunities: | Scholarships abroad - Research Internship - Doctorate (Direct) |
| Start date: | November 30, 2017 |
| End date: | November 29, 2018 |
| Field of knowledge: | Physical Sciences and Mathematics - Chemistry - Organic Chemistry |
| Principal Investigator: | Ronaldo Aloise Pilli |
| Grantee: | Franco Della Felice |
| Supervisor: | Michael J. Krische |
| Host Institution: | Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil |
| Institution abroad: | University of Texas at Austin (UT), United States |
| Associated to the scholarship: | 14/25474-8 - Synthesis and biological evualuation of Brevipolide A, Cryptomoskatone F1 and related compounds, BP.DD |
Abstract The research deals with the total syntheses of phosdiecin A, a polyketide isolated from from a culture of the marine Streptomyces sp. SS99BA-2 collected in São Sebastião Channel, Brazil. The interest to unravel the true identity of this molecule by total synthesis in collaboration with Prof. Krische from the University of Texas at Austin through catalytic asymmetric carbonyl addition methodologies developed by the Krische group, and to investigate the potential cytotoxic activity of these natural product, as well as of some intermediates and derivaitives to be prepared during this research, are the main reasons for presenting this proposal. (AU) | |
| News published in Agência FAPESP Newsletter about the scholarship: | |
| More itemsLess items | |
| TITULO | |
| Articles published in other media outlets ( ): | |
| More itemsLess items | |
| VEICULO: TITULO (DATA) | |
| VEICULO: TITULO (DATA) | |