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Comparison between the gut microbiome of healthy fish and fish experimentally infected with Streptococcus agalactiae

Grant number: 17/22288-7
Support type:Scholarships in Brazil - Master
Effective date (Start): March 01, 2018
Effective date (End): February 29, 2020
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
Principal Investigator:Wanderley Dias da Silveira
Grantee:Bruna Rafaela dos Santos Silva
Home Institution: Instituto de Biologia (IB). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Associated research grant:16/17421-7 - Comparison between the microbiomes of the respiratory tract of healthy chickens and chickens diagnosed with colibacillosis, AP.JP


Aquaculture is an economic activity that is soaring in the whole world, including Brazil. In this context, Nile tilapia (Oreochromis niloticus) has showed an increased potential, and has become the most raised species within Brazil. However, the expansion of fish-farming in Brazil is still not well managed. Fish-farming in Brazil presents high rates of deaths, mainly due to bacterial diseases and low sanitary and hygienic standards. Regarding tilapia husbandry, septicemia due to Streptococcus agalactiae is the disease with higher economic importance. This disease is chiefly characterized by the presence of meningoencephalitis. In this work, we aim to compare the gut microbiome of healthy animals and animals experimentally infected with S. agalactiae. Two distinct techniques will be employed, to evaluate bacteria attached to the intestinal epithelium, or free bacteria in the lumen. The microbiome will be established with next-generation sequencing (NGS). The reporting of microbiomes can, in the future, be useful for the establishment of measures to be adopted in order to control streptococcosis in fish-farms. (AU)

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SILVA, BRUNA RAFAELA DOS SANTOS; DERAMI, MARIANA SILVEIRA; PAIXAO, DOUGLAS ALVAREDO; PERSINOTI, GABRIELA FELIX; DIAS DA SILVEIRA, WANDERLEY; MALUTA, RENATO PARIZ. Comparison between the intestinal microbiome of healthy fish and fish experimentally infected with Streptococcus agalactiae. AQUACULTURE RESEARCH, v. 51, n. 8 MAY 2020. Web of Science Citations: 0.

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