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Identification of co-expression genes in Nellore cattle muscle tissue with divergent marbling and myofibrilar fragmentation index phenotypes, using RNA-seq data

Grant number: 18/11154-2
Support type:Scholarships abroad - Research Internship - Doctorate
Effective date (Start): September 03, 2018
Effective date (End): August 30, 2019
Field of knowledge:Agronomical Sciences - Animal Husbandry
Principal Investigator:Lucia Galvão de Albuquerque
Grantee:Maria Malane Magalhães Muniz
Supervisor abroad: Angela Canovas
Home Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil
Local de pesquisa : University of Guelph, Canada  
Associated to the scholarship:17/04270-3 - Study of transcriptoma of muscular tissue of Nelore breed bovine divergens for meat quality, BP.DR

Abstract

Meat quality traits are difficult to measure and not often included in current breedingprograms. However, due to the great economic importance of these traits, research toimprove our knowledge on the molecular factors and mechanisms that control theexpression of these traits is increasing. This project aims to evaluate the differential coexpressionof genes in Nellore bulls muscle tissue, within extreme groups formyofibrillar fragmentation index (MFI) and marbling phenotypes, using data fromtranscripts obtained by RNA-Seq. From this information, associations between theexpression of isoforms and the differential co-expression gene between the divergentgroups can be performed, which will produce a better understanding of the molecularmechanisms involved with marbling and tenderness related traits.