Analysis of the anti-inflammatory potential of green propolis against formalin-induced nociception

• Grant number: 18/00979-0
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: September 01, 2018
• End date: August 31, 2019
• Field of knowledge: Agronomical Sciences - Veterinary Medicine
• Principal Investigator: Ricardo Andrade Furtado
• Grantee: Vanessa de Souza Tótoli
• Host Institution: Pró-Reitoria Adjunta de Pesquisa e Pós-Graduação. Universidade de Franca (UNIFRAN). Franca , SP, Brazil
• Associated research grant: 17/04138-8 - Attainment of chemical, analytical, biological, pharmacological and technological studies to fill the gaps on the development of Brazilian propolis sector, AP.TEM

Abstract

Propolis is a phytobiotic resin from various plant sources that is collected and processed by bees. To your composition suffers variations according to the fabric of the region collected, season and even genetic traits of bees. In view of your great importance, the present work aims to evaluate the anti-inflammatory potential of green propolis extract and fractions in hexane, ethyl acetate, methanol and water in order to serve as directed study to assessing the phytochemical propolis extract provided for in the project 2017/04138-8. Therefore, the nociceptive and anti-inflammatory potential will be assessed through formalin test. Therefore, this work will assist to better understanding and use of green propolis.