Molecular evolution and genetic diversity of toxins in Nemertea

• Grant number: 18/12502-4
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: November 01, 2018
• End date: June 30, 2020
• Field of knowledge: Biological Sciences - Zoology - Applied Zoology
• Principal Investigator: Sónia Cristina da Silva Andrade
• Grantee: Gabriel Gonzalez Sonoda
• Host Institution: Instituto de Biociências (IB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 15/20139-9 - Seascape genetics and evaluation of expression profiles on marine invertebrates on Brazilian Southeast coast, AP.JP

Abstract

Nemertea is a phylum of vermiform animals, most marine and carnivores. These animals are armed with toxins, which they use both for predation and defense. However, little is known about the diversity of toxins present within this clade or about the exact function of these toxins in the biology of many of their representants. This study aims to identify if there is genetic variability in three candidate genes that code toxins in Nemertean that inhabit the Brazilian Coast and describe their intra and interspecific diversity. Molecular evolution analysis will be performed to estimate if natural selection has had a role on these genes variation throughout their evolution. To do so, five species shall be analyzed, four of which will be collected at Northern Coast of São Paulo State (Lineus bonaerensis, Nemertopsis bivitatta, Ototyphlonemertes lactea and O. erneba), and Cerebratulus lineolatus, which specimens have been previously collected in Ceará State.