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Longitudinal impact of athletic practice on bone health, metabolism and inflammation of adolescents: ABCD-GROWTH study

Grant number: 18/09230-2
Support Opportunities:Scholarships in Brazil - Master
Effective date (Start): November 01, 2018
Effective date (End): September 27, 2020
Field of knowledge:Health Sciences - Physical Education
Acordo de Cooperação: Coordination of Improvement of Higher Education Personnel (CAPES)
Principal Investigator:Rômulo Araújo Fernandes
Grantee:Yuri da Silva Ventura Faustino da Silva
Host Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil
Associated scholarship(s):19/15959-8 - Impact of biological maturation as a potentiating agent of bone gains resulting from sports participation among adolescents: ABCD growth study, BE.EP.MS


Introduction: The literature has sought to understand the effects of sports practice on health components, especially in pediatric populations aimed at reducing the risk of developing chronic diseases in adulthood. Impact sports, practiced during adolescence, have shown propulsive effects on the development of bone tissue, especially in bone mineral density. However, some modalities, such as athletics, although apparently covering the characteristics necessary to promote bone health (jumping, running, changes of direction, besides sun exposure), the literature is still scarce of information about the effect of the modality on bone health . Objective: To analyze the effect of athletic practice on the bone tissue, metabolic and inflammatory profile in adolescents of both sexes during a period of 12 months. Methods: This project, with a longitudinal observational design, aims to accompany adolescents during 12 months (baseline [0] and 12 months [i]), being conducted in the city of Presidente Prudente - SP. Sample will be composed of adolescents between 11 and 18 years old, divided into two distinct groups: I) Control (adolescents not practicing sports modalities systematized) and II) Athletic group (adolescents practicing athletics for at least 1 year). In addition to the other specific inclusion criteria that will be adopted for each group. Will be analyzed for study outcomes: I) Dependent Variable: Bone mineral density and bone mineral content, analyzed by dual energy x-ray absorptiometry (DXA); II) Independent Variable: i- anthropometric (weight, stature, fat mass, fat-free mass and bone), ii- Serum Variables (vitamin D, Calcium, Triglycerides, HDL, LDL, of Training Load; Confusion variable: i- age, ii- sex, iii - somatic maturation. Statistical significance will be set at p <0.05 and all analyzes will be performed using Stata 15.1 (Texas, USA).

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
FAUSTINO-DA-SILVA, V, YURI; MARTINHO, V, DIOGO; COELHO-E-SILVA, MANUEL J.; VALENTE-DOS-SANTOS, JOAO; CONDE, JORGE; OLIVEIRA, TOMAS G.; RONQUE, V, ENIO R.; AGOSTINETE, RICARDO R.; FERNANDES, ROMULO A.; SHERAR, LAUREN B.. Reproducibility and inter-observer agreement of Greulich-Pyle protocol to estimate skeletal age among female adolescent soccer players. BMC PEDIATRICS, v. 20, n. 1, . (18/09230-2, 19/15959-8)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
SILVA, Yuri da Silva Ventura Faustino da. Longitudinal impact of athletics on bone health, metabolism and inflammation in adolescents: ABCD-growth study. 2020. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Ciências e Tecnologia. Presidente Prudente Presidente Prudente.

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