Impact of vitamin D on markers of bone metabolism, bone mineral density, insulin secretion and blood pressure of adolescents practicing six different sports modalities: ABCD: growth study

• Grant number: 19/03478-5
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: July 01, 2019
• End date: August 31, 2020
• Field of knowledge: Health Sciences - Physical Education
• Principal Investigator: Rômulo Araújo Fernandes
• Grantee: Eduardo Duarte de Lima Mesquita
• Host Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil

Abstract

Introduction: Vitamin D plays an important role in bone formation, being strongly used in the reabsorption of calcium, however little is known about the impact of vitamin D in relation to the increase of bone tissue in adolescents, practitioners of different sports modalities, as well such as its impact on insulin secretion and blood pressure control. Objective: To identify the impact of vitamin D on markers of bone metabolism, bone mineral density, insulin secretion and blood pressure of adolescents practicing six different sports modalities. Methods: A 12-month follow-up longitudinal study conducted in the city of Presidente Prudente. The sample will be composed of at least 236 adolescents practicing different modalities. Vitamin D, calcium, CTX, osteocalcin and insulin will be measured by blood analysis, while bone mineral density, fat mass and soft and lean tissue will be estimated by means of dual energy X-ray absorptiometry in different segments, blood pressure will be measured using the oscillometric method using an automatic device. Expected Results: It is expected to identify if vitamin D has an impact on bone health and impact on insulin secretion and adolescent blood pressure independent of the biomechanics of the modality.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE LIMA MESQUITA, EDUARDO DUARTE; EXUPERIO, ISABELLA NETO; AGOSTINETE, RICARDO RIBEIRO; LUIZ-DE-MARCO, RAFAEL; MIGUEL DA SILVA, JESSICA CASAROTTI; MAILLANE-VANEGAS, SANTIAGO; KEMPER, HAN C. G.; FERNANDES, ROMULO ARAUJO. The Combined Relationship of Vitamin D and Weight-Bearing Sports Participation on Areal Bone Density and Geometry Among Adolescents: ABCD-Growth Study. JOURNAL OF CLINICAL DENSITOMETRY, v. 25, n. 4, p. 8-pg., 2022-10-01. (20/09496-2, 17/09182-5, 19/22754-3, 19/03478-5, 18/24164-6, 18/22593-7, 19/09297-2)