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Purification of milk proteins at pilot scale using membrane filtration and preparative chromatography

Grant number: 18/24481-1
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): February 01, 2019
Effective date (End): January 19, 2020
Field of knowledge:Agronomical Sciences - Food Science and Technology - Food Science
Principal researcher:Guilherme Miranda Tavares
Grantee:Heice Silva Lopes Moraes
Home Institution: Faculdade de Engenharia de Alimentos (FEA). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Associated research grant:17/09214-4 - How do structural changes of dairy proteins affect the functionality of bioactive compounds in complex food matrices?, AP.JP


The purification of high value-added macromolecules from food matrices represents a great opportunity to diversify activities of food industries. Despite the great accumulated knowledge about milk proteins, their large-scale purification usually does not preserve their native structure, which is crucial for their techno-functionalities. Thus, the objective of the present work is to develop protocols for the purification of globular milk proteins preserving their native structure through the association of tangential filtration techniques and preparative liquid chromatography.

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