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Acute autonomic responses of virtual reality based therapy in comparison with conventional cardiac rehabilitation

Grant number: 18/18276-6
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): April 01, 2019
Effective date (End): December 31, 2019
Field of knowledge:Health Sciences - Physiotherapy and Occupational Therapy
Principal researcher:Luiz Carlos Marques Vanderlei
Grantee:Paula Fernanda da Silva
Home Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil


Cardiovascular rehabilitation programs (CR) can promote several benefits in patients with cardiac diseases. However, there are problems related to the patient adherence in CR. Some of these problems can be caused to factors like motivation. Alternative therapies can improve motivation and increase adherence to CR. In this context, virtual reality based therapy (VRBT), have shown benefits in cardiac patients to pain relief, functional capacity and increasing physical activity levels, but there is no answer whether the acute responses of VRBT can be similar from the conventional one. Objective: investigate autonomic responses of VRBT in comparison with conventional therapy (CT). Methods: patients with cardiac diseases or risk factors will be invited to perform CT or VRBT+CT. They will be submitted to an initial evaluation, the intervention and to a final evaluation. The initial evaluation include eligibility investigation, and after they will be random allocated to the interventions. The interventions will be performed with a frequency of three times a week, for 12 weeks, and the intensity will be prescribed individually. Autonomic responses will be evaluated before, during and after a session at the first and twelfth week using heart rate variability. The heart rate variability will be measured through the following linear indices (SDNN: the standard deviation of normal-to-normal intervals, ms; rMSSD: the root mean square of successive difference between normal intervals,ms; LF: low frequency, nu; HF: high frequency and nonlinear indices,nu.). In addition the nonlinear indices will be measured (SD1: standard deviation of instant variability beat to beat; SD2: standard deviation of long-term interval between consecutive heart beats). In general higher values represent a better autonomic response. Statistical analysis: the data analysis will be evaluated using the two way ANOVA with Bonferroni posttest with significance to p < 0.05.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SILVA, PAULA F.; RICCI-VITOR, ANA LAURA; CRUZ, MAYARA M.; BORGES, GIOVANNA L.; GARNER, DAVID M.; MARQUES VANDERLEI, LUIZ C.. Comparison of acute response of cardiac autonomic modulation between virtual reality-based therapy and cardiovascular rehabilitation: a cluster-randomized crossover trial. PHYSIOTHERAPY THEORY AND PRACTICE, . (18/18276-6)
GIOVANNA LOMBARDI BONINI BORGES; MAYARA MOURA ALVES DA CRUZ; ANA LAURA RICCI-VITOR; PAULA FERNANDA DA SILVA; SHERRY LYNN GRACE; LUIZ CARLOS MARQUES VANDERLEI. Publicly versus privately funded cardiac rehabilitation: access and adherence barriers. A cross-sectional study. São Paulo Medical Journal, v. 140, n. 1, p. 108-114, . (18/18276-6)

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