Modular biosensors based on electrolyte gated organic field effect transistors with polyaniline thin films

• Grant number: 18/22223-5
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): April 01, 2019
• Effective date (End): May 31, 2020
• Field of knowledge: Interdisciplinary Subjects
• Principal Investigator: Marcelo Mulato
• Grantee: Murilo Calil Faleiros
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated research grant: 17/24839-0 - Nanoelectronics and nanoscale electrochemistry: fundaments and applications, AP.TEM

Abstract

The necessity to quantify analytes of biological interest encouraged the search for development of devices called biosensors. These devices must be capable of converting biological signals into measurable electrical signals, keeping the sensor selectivity with the interest analyte. Preferably they must be biocompatible. Field effect transistors are solid state devices with potential use in biosensors. Aiming the biocompatibility, these transistors may have they structure changed, utilizing an organic semiconductor polymer instead of an inorganic semiconductor, making it an Organic Field Effect Transistor. These transistors can be modified through the externalization of their gate electrode, now submerged into an electrolyte solution. In this architecture, the interest analyte is recognized through immobilization of molecules in the polymer surface or in the gate electrode surface, making this last approach of great interest, resulting in a modular device to recognize analytes. This project has as main goal the fabrication of Electrolyte Gate Organic Field Effect Transistor, to use it as biosensor in analytes of interest, utilizing the polyaniline polymer as organic semiconductor.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MADEIRA, GUSTAVO DANIEL M.; DIAS MELLO, HUGO JOSE N. P.; FALEIROS, MURILO C.; MULATO, MARCELO. Model improvement for super-Nernstian pH sensors: the effect of surface hydration. Journal of Materials Science, v. 56, n. 3, p. 2738-2747, JAN 2021. (18/24395-8, 14/24559-0, 18/22223-5, 17/24201-6)