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Effect of sentinel lymph node biopsy on upper limb function in women with early breast cancer compared to axillary dissection: systematic review

Grant number: 18/15817-6
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): June 01, 2019
Effective date (End): July 31, 2020
Field of knowledge:Health Sciences - Medicine - Surgery
Principal Investigator:Francisco José Candido dos Reis
Grantee:Taynara Louisi Pilger
Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil


Sentinel lymph node biopsy (BLS) and axillary dissection (AD) are interventions used to staging women with breast cancer. These interventions are associated with varying degrees of dysfunction of the upper limb on the side affected by the disease. Physiotherapeutic techniques are used to prevent and / or treat such dysfunctions, however it is fundamental to estimate the risk and factors associated with such occurrences. Our objective is to perform a systematic review of the literature to estimate the risk of occurrence of upper limb dysfunctions associated with BLS and AS. The research will be developed through articles on the subject available in databases, PUBMED, WEB OF SCIENCE, EMBASE and CINAHL by the year 2018. The research strategy will include controlled vocabulary (MeSH) and key words Sentinel Lymph Node Biopsy; Breast Cancer, Axillary Dissection; and additional key words Lymphedema, Lymphoedema, Breast Neoplasm, Side effects, Sequels, Pain and Musculoskeletal events.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
PILGER, TAYNARA LOUISI; FRANCISCO, DANIELY FRANCO; DOS REIS, FRANCISCO JOSE CANDIDO. Effect of sentinel lymph node biopsy on upper limb function in women with early breast cancer: A systematic review of clinical trials. EJSO, v. 47, n. 7, p. 1497-1506, . (18/15817-6)

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