Synthesis and characterization of polymeric modified scaffold with a bioactive molecule

• Grant number: 19/05566-9
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: May 01, 2019
• End date: June 30, 2020
• Field of knowledge: Engineering - Biomedical Engineering - Bioengineering
• Principal Investigator: Carla dos Santos Riccardi
• Grantee: Ananda Beatriz Passeto de Oliveira
• Host Institution: Faculdade de Ciências Agronômicas (FCA). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil

Abstract

Tissue engineering provides a prospective new strategic by clinical applications to promote the regeneration of damaged or diseased tissues using biomaterials. In this work, a biocompatible polymer scaffold will be developed by solvent evaporation process. The scaffolds will be obtained under planar membrane mold and tubular prototypes. The project aims to obtain a device with antimicrobial, hemostatic properties and optimize aspects of flexibility. Therefore, morphological, physic-chemical, mechanical and biological properties will be characterized. The device is expected to exhibit distinct mechanical properties for suture fixation and application as vascular grafts.