Impact of capsaicin supplementation associated with aerobic physical training on visceral adipose tissue

• Grant number: 19/05295-5
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): August 01, 2019
• Effective date (End): August 31, 2022
• Field of knowledge: Health Sciences - Physical Education
• Principal Investigator: Fábio Santos de Lira
• Grantee: Vinicius Aparecido Matos Soares
• Host Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil

Abstract

A high percentage of body fat is directly related to the excess of absorbed and unused calories and the consumption of high fat diets is related to the accumulation of adipose tissue, especially visceral, and that regular physical exercise is an important strategy to attenuate the accumulation. In addition, some ergogenic resources have been studied to improve body composition, being: taurine, caffeine and recently capsaicin. Capsaicin is a natural substance found in peppers and due to its thermogenic, neural effects and high lipid oxidation, has been studied as a nutritional strategy for weight loss. In addition, it is already well established the increase in energy expenditure provided by aerobic exercise resulting in the reduction of body weight, and capsaicin, which also promotes a greater energy expenditure, enhances this effect. The objective of this study will be to evaluate the effectiveness of capsaicin supplementation associated with high intensity aerobic physical training on the percentage of body fat in trained youth. The experimental design of the present study will be double-blind placebo controlled. Participants will perform 12 weeks of high intensity intermittent aerobic physical training. A maximum incremental test will be performed on the treadmill to estimate the maximum oxygen consumption (VO2max) and the body composition evaluation will be by electrical bioimpedance, DEXA and ultrasonography. Subsequently, participants will be randomized into two groups (capsaicin 12 mg) and placebo (starch 12 mg), both groups will perform intermittent high intensity exercise (100% maximum aerobic velocity, 1: 1 and total volume 5 km) with double-blind study. For statistical treatment, a two-way Shapiro-Wilk test and analysis of variance will be performed to compare moments (pre and post intervention), analyzed by SPSS software (version 22.0).

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

VON AH MORANO, ANA ELISA; PADILHA, CAMILA S.; SOARES, VINICIUS APARECIDO MATOS; ANDRADE MACHADO, FABIANA; HOFMANN, PETER; ROSSI, FABRICIO E.; LIRA, FABIO SANTOS. Capsaicin Analogue Supplementation Does Not Improve 10 km Running Time-Trial Performance in Male Amateur Athletes: A Randomized, Crossover, Double-Blind and Placebo-Controlled Study. NUTRIENTS, v. 13, n. 1, JAN 2021. (19/05295-5)