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Evaluation of the interaction of soforolipid biosurfactant with phospholipid membrane models

Grant number: 19/19757-0
Support type:Scholarships abroad - Research Internship - Post-doctor
Effective date (Start): January 27, 2020
Effective date (End): January 26, 2021
Field of knowledge:Biological Sciences - Biophysics - Molecular Biophysics
Principal researcher:Silvio Silvério da Silva
Grantee:Paulo Ricardo Franco Marcelino
Supervisor abroad: Antonio Ortiz Lopez
Home Institution: Escola de Engenharia de Lorena (EEL). Universidade de São Paulo (USP). Lorena , SP, Brazil
Research place: Universidad de Murcia, Spain  
Associated to the scholarship:16/14852-7 - A sustainable solution against neglected tropical diseases using biosurfactants produced by yeasts in sugarcane bagasse hemicellulosic hydrolyzate, BP.PD

Abstract

Brazil has been experiencing a moment of extreme attention in public health and agriculture. Cases of dengue, chikungunya and zika have increased vertiginously year after year, causing concern in the public health authorities and society. In addition, recently, the Brazilian government has released the use of some pesticides with toxicity relevant to living things and the environment. The search for solutions to overcome these problems has found some biotechnological alternatives, such as biosurfactants, considered ecologically correct products with potential larvicide. The present work aims to complement the studies of the project FAPESP 2016/14852-7, which uses the sophorolipid biosurfactants produced by Scheffersomyces stipitis in sugarcane bagasse hemicellulosic hydrolysate as larvicides against Aedes aegypti. Preliminary results have shown that the use of these biosurfactants may also be effective against some pests of agricultural interest. Thus, the present proposal aims to evaluate the interaction of sophorolipid biosurfactant with artificial membranes, helping to understand the larvicidal effect of these biomolecules and the further development of sustainable biotechnological products.

News published in Agência FAPESP Newsletter about the scholarship:
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
PHILIPPINI, RAFAEL RODRIGUES; MARTINIANO, SABRINA EVELIN; INGLE, AVINASH P.; FRANCO MARCELINO, PAULO RICARDO; SILVA, GILDA MARIANO; BARBOSA, FERNANDA GONCALVES; DOS SANTOS, JULIO CESAR; DA SILVA, SILVIO SILVERIO. Agroindustrial Byproducts for the Generation of Biobased Products: Alternatives for Sustainable Biorefineries. FRONTIERS IN ENERGY RESEARCH, v. 8, JUL 29 2020. Web of Science Citations: 0.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.