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Salmonella and Cronobacter sakazakii in milk and infant formula: behavior during spray drying and determination of inactivation parameters based on single droplet approach

Grant number: 19/16209-2
Support Opportunities:Scholarships in Brazil - Post-Doctoral
Start date: October 01, 2020
End date: October 31, 2024
Field of knowledge:Health Sciences - Collective Health - Public Health
Principal Investigator:Anderson de Souza Sant'Ana
Grantee:Emilie Lang
Host Institution: Faculdade de Engenharia de Alimentos (FEA). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Associated scholarship(s):22/14938-0 - Salmonella enterica and Cronobacter sakazakii: both pathogens of powdered infant formula: an omic compartive study to understand their behavior along the food production chain, BE.EP.PD

Abstract

In December 2017, the world has been following news stories about the occurrence of an outbreak caused by Salmonella Agona linked to infant formulas produced by a company located in France. This outbreak resulted in a massive recall and destruction of more than 12 million packages of infant formulas, shook consumer's confidence and, raised questions about the processing practices adopted by food industries as contamination occurred in spray-drying tower. The microbiological safety of milk powder has a central importance in public health, since it has diverse applications in the food industry, including the manufacture of infant formulas which is consumed by children, who are extremely susceptible to microbial infections. Salmonella and Cronobacter sakazakii are frequently associated with foodborne diseases involving these products likely because of their ability to adapt and survive in dry foods. Despite this, it is unknown until now, if and how these microorganisms can survive the process of spray-drying, which involves mass and heat transfer. The present project aims to study the survival of Salmonella and Cronobacter sakazakii to spray-drying especially after sub-lethal heat and/or desiccation stresses. More than a global spray-drying process and for the first time, it is proposed to use the single droplet drying technique to understand and determine the parameters leading to the inactivation of these two foodborne pathogens. These data will complete the fundamental knowledge on these two pathogens but will also find direct practical applications to ensure microbial safety of foods, furnishing either spray-drying parameters to control for the milk powder and infant formulas processing industries and establishment of scientifically-based and effective control for health authorities. (AU)

News published in Agência FAPESP Newsletter about the scholarship:
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
LANG, EMILIE; SANT'ANA, ANDERSON S.. Microbial contaminants in powdered infant formula: what is the impact of spray-drying on microbial inactivation?. CURRENT OPINION IN FOOD SCIENCE, v. 42, p. 195-202, . (19/16209-2)