Abrasive potential of dentifrices containing activated charcoal on dentin eroded: in vitro study

• Grant number: 21/06143-4
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: September 01, 2021
• End date: October 31, 2023
• Field of knowledge: Biological Sciences - Biochemistry
• Principal Investigator: Ana Carolina Magalhães
• Grantee: Júlia França da Silva
• Host Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil
• Associated scholarship(s): 22/13803-3 - Volumetric analysis of substance loss of rat's teeth submitted or not to erosive challenges and to previous treatment with TiF4 varnish, BE.EP.IC

Abstract

This in vitro work aims to evaluate the abrasive effect of toothpaste containing activated carbon on the erosive dentin wear. For this, 132 dentin samples will be prepared from bovine incisors, which will be distributed into the following groups: Group 1 - Colgate Triple Action (positive control); Group 2 - Colgate Natural Extracts; Group 3 - Colgate Luminous White Activated Carbon; Group 4 - Oral-B Whitening Therapy Charcoal; Group 5 - Oral-B 3D White Mineral Clean (n = 24 for all dentifrices) and Group 6 - Erosion only (without abrasion) (negative control) (n = 12). The samples will be subjected to pH cycling (4 x 90 s/day in 0.1% citric acid, pH 2.5) and to the abrasive challenge (2 x 15 s/day abrasion + 45 s of treatment), using a brushing machine for 7 days. Among the erosive and abrasive challenges, the samples will be immersed in artificial saliva. Dentin wear will be quantified by contact profilometry (¼m) by comparing the initial profile and the final profile. The data will be statistically compared considering p <0.05. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

VERTUAN, MARIELE; DA SILVA, JULIA FRANCA; DE OLIVEIRA, ANA CLARA MOTA; DA SILVA, THAYNA TEODORO; JUSTO, ANDREZA PERES; ZORDAN, FERNANDA LAUDARES SILVA; MAGALHAES, ANA CAROLINA. The in vitro Effect of Dentifrices With Activated Charcoal on Eroded Teeth. INTERNATIONAL DENTAL JOURNAL, v. 73, n. 4, p. 6-pg., 2023-08-01. (21/06143-4, 19/21797-0)