Advanced search
Start date

Evaluation of isolated and associated Proanthocyanidin and vitamin E in preventing initial enamel erosion

Grant number: 21/11038-5
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): December 01, 2021
Effective date (End): May 31, 2023
Field of knowledge:Health Sciences - Dentistry - Pediatric Dentistry
Principal Investigator:Daniela Rios Honório
Grantee:Julia Fiorese Sabino
Host Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil


This in vitro study will evaluate the effectiveness of isolated and associated Proanthocyanidin and Vitamin E in preventing initial enamel erosion. Bovine tee the name blocks will be divided into 9 studied groups (n= 12): G1- Elmex Erosionprotection (positive control), G2- Deionized water (negative control), G3- 6.5%Proanthocyanidin, G4- 2% Proanthocyanidin, G5- 100% oily Vitamin E, G6- 100% oily Vitamin E + 6.5% Proanthocyanidin, G7- 6.5% Proanthocyanidin + 100% oily Vitamin E, G8- 100% oily Vitamin E + 2% Proanthocyanidin, G9- 2% Proanthocyanidin + 100%oily Vitamin E. The acquired enamel pellicle will be formed in situ by an intraoral palatal device containing the enamel blocks. The treatment will be carried out by applying the solutions for 30 seconds. After that, the enamel blocks will be demineralized by citric acid (0.5%, pH 2.5) for 30 seconds. Then, they will be rinsed in deionized water to cease the demineralization process. The response variable will be a percentage of hardness loss by evaluating the initial (before treatment) and final (after the initial erosion) hardness. Data will be checked for normality and homogeneity. If they pass these tests, they will be submitted to ANOVA followed by Tukey's test (p<0.05). (AU)

News published in Agência FAPESP Newsletter about the scholarship:
Articles published in other media outlets (0 total):
More itemsLess items

Please report errors in scientific publications list by writing to: