Hydrophobic Deep Eutectic Solvents (hDES) Applied to Remove Emerging and Inorganic Contaminants in Environmental Samples

• Grant number: 21/14581-1
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: June 01, 2022
• End date: May 31, 2025
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Mario Henrique Gonzalez
• Grantee: Rafaela Silva Lamarca
• Host Institution: Instituto de Biociências, Letras e Ciências Exatas (IBILCE). Universidade Estadual Paulista (UNESP). Campus de São José do Rio Preto. São José do Rio Preto , SP, Brazil
• Associated research grant: 14/50945-4 - INCT 2014: National Institute for Alternative Technologies of Detection, Toxicological Evaluation and Removal of Micropollutants and Radioactivies, AP.TEM

Abstract

recent decades, population growth and the growing expansion in the use ofdrugs, endocrine disruptors, flame retardants and personal care and cleaningproducts have brought harm to aquatic life and impacted human health. Thepresence of these emerging contaminants (ECs) in wastewater and surface water,mainly as a result of human activity, negatively impacts the ecosystems involved,in addition to inducing endocrine disturbances in humans. Thus, the developmentof solvents and new green and sustainable methodologies for the removal of thesecontaminants are extremely important and are the focus of Green AnalyticalChemistry (GAC). This research project proposes the development of hydrophobicdeep eutectic solvents (hDES) for ECs removal. The hDES will be synthesized bycombining mixtures based on DL-menthol, lactic acid and acetic acid, employing amixture planning to optimize the best proportions of the precursors. These newsolvents will be used to extract bisphenol A, bisphenol S, polybrominated diphenylethers from wastewater samples and determine them by gas chromatographycoupled to mass spectrometry (GC/MS). A second stage of the project will aim atmodifying hDES with magnetic nanoparticles, previously prepared by coprecipitation,aiming at the removal of inorganic contaminants such as As, Cd, Cu,Hg, Pb and Zn in sewage sludge samples from a plastic industry. Thedetermination of these contaminants will be carried out by inductively coupledplasma mass spectrometry (ICP-MS), where it is expected to obtain solvents withhigh removal capacity for use in environmental matrices. This project will aim atthe development and production of a new class of sustainable green solvents andthe evaluation of its application in environmental matrices. It is expected to obtainsolvents with high capacity to remove different chemical contaminants, in additionto the development of new sustainable materials and applicable in chemicalanalysis.

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LAMARCA, RAFAELA S.; DOS S. FERREIRA, SABRINA; ABUCAFY, MARINA P.; SILVA, LEANDRO S.; PISHRO, KHATEREH A.; AMARAL, CLARICE D. B.; FERNANDES, JOSE O.; CUNHA, SARA C.; FRANCO, DOUGLAS F.; GONZALEZ, MARIO H.. Advances in Sustainable Extraction of Arsenic and Cadmium from Sewage Sludge: Use of Hydrophobic Deep Eutectic Solvent Modified with Magnetic Nanoparticles. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, v. 12, n. 39, p. 9-pg., 2024-09-16. (21/14759-5, 23/04832-2, 21/14581-1, 14/50945-4)

LAMARCA, RAFAELA S.; FERREIRA, SABRINA DOS S.; PAGANINI, EDER R.; FERREIRA, NATHALIA DOS S.; AYALA-DURAN, SAIDY C.; ISQUIBOLA, GUILHERME; GOMES, PAULO C. F. DE LIMA; AMARAL, CLARICE D. B.; MAGNANI, MARINA; FRANCO, DOUGLAS F.; et al. Sustainable cadmium extraction from sewage sludge samples: A novel approach with hydrophobic deep eutectic solvents and ultrasound-assisted extraction (HDES-UAE) prior to ICP-MS analysis. JOURNAL OF MOLECULAR LIQUIDS, v. 398, p. 9-pg., 2024-02-19. (21/14581-1, 14/50945-4, 21/14759-5, 19/22113-8, 17/18531-3, 23/04832-2)

FERREIRA, SABRINA S.; BRITO, THOMAS A.; SANTANA, ANA P. R.; GUIMARAES, TACIANA G. S.; LAMARCA, RAFAELA S.; FERREIRA, KAREN C.; GOMES, PAULO C. F. LIMA; OLIVEIRA, ANDREA; AMARAL, CLARICE D. B.; GONZALEZ, MARIO H.. Greenness of procedures using NADES in the preparation of vegetal samples: Comparison of five green metrics. TALANTA OPEN, v. 6, p. 7-pg., 2022-12-01. (21/14581-1, 19/22113-8, 14/50945-4, 15/08873-9, 17/18531-3)

LAMARCA, RAFAELA SILVA; SILVA, JOAO PEDRO; DOS SANTOS, JOAO PAULO VARONI; AYALA-DURAN, SAIDY CRISTINA; GOMES, PAULO CLAIRMONT FEITOSA DE LIMA. Modular 3D-printed fluorometer/photometer for determination of iron(ii), caffeine, and ciprofloxacin in pharmaceutical samples. RSC ADVANCES, v. 13, n. 18, p. 9-pg., 2023-04-17. (21/14581-1, 22/02991-3, 14/50945-4, 18/22393-8)