The basal metabolic rate in the pre and postoperative period of bariatric surgery: influence of environmental, clinical and nutritional factors

• Grant number: 23/00605-1
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: March 01, 2023
• End date: December 31, 2023
• Field of knowledge: Health Sciences - Nutrition - Nutritional Analysis of Population
• Principal Investigator: Carla Barbosa Nonino
• Grantee: Lucca Cintra do Prado Assumpção
• Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

The basal metabolic rate (BMR) is defined as the amount of energy required for the normal physiological maintenance of the organism at rest. Usually, the calculations used to measure BMR are based on individuals without obesity according to the Body Mass Index (BMI) classification. However, when this method is extrapolated to patients with obesity, the accuracy rate decreases considerably. Due to this possible discrepancy between the predictive formulas and the actual individual BMR, the use of indirect calorimetry (IC) in individuals with obesity, especially severe obesity, is essential, in which patients are candidates for bariatric surgery. Thus, the importance of studies that deepen the analysis of IC for this population is highlighted, considering the pre and postoperative period of bariatric surgery. This study aims to identify the environmental, clinical and nutritional factors that could influence BMR in the pre and postoperative period (6 months) of bariatric surgery. Clinical (anthropometry and body composition by IC), environmental (smoking, alcoholism, family history of obesity, physical activity, medication use, exposure to heavy metals such as arsenic, mercury and cadmium) and nutritional (food intake) data from patients submitted to bariatric surgery in the preoperative period and 6 months after the procedure, will be selected. For data analysis, the following tests will be applied: Shapiro-Wilk, Pearson or Spearman, and paired t-test or Wilcoxon, using SPSS 21 and GraphPad Prism software. P values <0.05 will be considered significant.