Longitudinal evaluation of microstructural alterations of the corpus callosum in cSLE: Association with clinical and laboratory manifestations, NR-2 subunit of the N-methyl-D-aspartate receptor, cytokines, anti-ribosomal P antibody and IFN-alpha activity.

• Grant number: 25/13397-3
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: October 01, 2025
• End date: September 30, 2028
• Field of knowledge: Biological Sciences - Immunology - Cellular Immunology
• Principal Investigator: Simone Appenzeller
• Grantee: Samara Rosa Sepresse
• Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 13/07559-3 - BRAINN - The Brazilian Institute of Neuroscience and Neurotechnology, AP.CEPID

Abstract

Childhood-onset Systemic Lupus Erythematosus (cSLE) is an autoimmune disease that can cause systemic involvement, including the central nervous system (CNS).