Study of porous implants osseointegration: analysis of bone growth in pores, resistance of implant-bone interface and mechanical property of porous titanium

• Grant number: 05/03709-4
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: January 01, 2006
• End date: December 31, 2008
• Field of knowledge: Health Sciences - Dentistry
• Principal Investigator: Carlos Alberto Alves Cairo
• Grantee: Luana Marotta Reis de Vasconcellos
• Host Institution: Instituto de Aeronáutica e Espaço (IAE). Departamento de Ciência e Tecnologia Aeroespacial (DCTA). Ministério da Defesa (Brasil). São José dos Campos , SP, Brazil

Abstract

The aim of this study will be to evaluate and to compare the repair and strength of the bone tissue around the porous cylindrical implants which will be made of powder metallurgy. Histological analysis, histomorphometric analysis, and mechanical test will be carried. The materials used will be: powder of commercially pure titanium, oil ether, and polyethylene presenting granule with diameter between 250μm and 350μm. The implants will be divided in three groups according to the percentage of polyethylene presented. That percentage could change from 10% to 30%. Following the implants will be characterized by means of metallographic analysis and they will be submitted to a compression strength test to evaluate their mechanical property. Afterwards the implants will be placed in thirty rabbits, which will receive three porous implants, being one of each group, in the right and left tibia. Fifteen rabbits, which will be selected randomly, will be sacrificed in 08 and 12 weeks after the surgery. The animals will be subdivided in two groups, being that six rabbits will be submitted to the histological and histomorphometric analysis to evaluate the new bone formation in the implant-bone interface and nine rabbits will be submitted to push-out test to check the fixation of implants to bone. The data obtained from the histomorphometric analysis, push-out test, and compression strength test will be submitted to ANOVA test and TUKEY test.

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LUANA MAROTTA REIS DE VASCONCELLOS; DANIEL OLIVEIRA LEITE; FERNANDA NASCIMENTO DE OLIVEIRA; YASMIN RODARTE CARVALHO; CARLOS ALBERTO ALVES CAIRO. Evaluation of bone ingrowth into porous titanium implant: histomorphometric analysis in rabbits. Brazilian Oral Research, v. 24, n. 4, p. 399-405, 2010-12-00. (05/03709-4)

DO PRADO, RENATA FALCHETE; OLIVEIRA DE VASCONCELLOS, LUIS GUSTAVO; REIS DE VASCONCELLOS, LUANA MAROTTA; ALVES CAIRO, CARLOS ALBERTO; LEITE, DANIEL DE OLIVEIRA; DOS SANTOS, ALESSANDRA; CARDOSO JORGE, ANTONIO OLAVO; ROMEIRO, ROGERIO DE LIMA; BALDUCCI, IVAN; CARVALHO, YASMIN RODARTE. In Vivo Osteogenesis and In Vitro Streptococcus mutans Adherence: Porous-Surfaced Cylindrical Implants vs Rough-Surfaced Threaded Implants. INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS, v. 28, n. 6, p. 1630-1638, NOV-DEC 2013. (05/03709-4)

REIS DE VASCONCELLOS, LUANA MAROTTA; OLIVEIRA, FERNANDA NASCIMENTO; LEITE, DANIEL DE OLIVEIRA; OLIVEIRA DE VASCONCELLOS, LUIS GUSTAVO; DO PRADO, RENATA FALCHETE; RAMOS, CAROLINA JUDICA; DE ALENCASTRO GRACA, MARIO LIMA; ALVES CAIRO, CARLOS ALBERTO; CARVALHO, YASMIN RODARTE. Novel production method of porous surface Ti samples for biomedical application. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, v. 23, n. 2, p. 357-364, FEB 2012. (05/03709-4)

LUANA MAROTTA REIS DE VASCONCELLOS; RODRIGO DIAS NASCIMENTO; CARLOS ALBERTO ALVES CAIRO; DANIEL DE OLIVEIRA LEITE; EVELYN LUZIA DE SOUZA SANTOS; GABRIELA ESTEVES CAMPOS; RENATA FALCHETE DO PRADO; MARIA APARECIDA NEVES JARDINI; LUIS GUSTAVO OLIVEIRA DE VASCONCELLOS; YASMIN RODARTE CARVALHO. Porous Titanium Associated with CaP Coating: In Vivo and In Vitro Osteogenic Performance. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 21, n. 2, 2017-12-18. (05/03709-4, 07/08593-0)