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Morita-Baylis-Hillman reaction in the asymmetric synthesis of 3-pirrolizinone

Grant number: 10/08336-0
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): August 01, 2010
Effective date (End): July 31, 2011
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Organic Chemistry
Principal researcher:Fernando Antonio Santos Coelho
Grantee:Hugo dos Santos
Home Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

This undergraduate research project has as main target the preparation of a chiral synthetic intermediate to be used in the total synthesis of pirrolizidinic alkaloids, from a chiral Morita-Baylis-Hillman adduct. The latter will be prepared from a natural aminoacid. (AU)

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