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The association between dietary patterns and bone mineral density in postmenopausal women with osteoporosis

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Author(s):
Natasha Aparecida Grande de França
Total Authors: 1
Document type: Master's Dissertation
Press: São Paulo.
Institution: Universidade de São Paulo (USP). Faculdade de Saúde Pública (FSP/CIR)
Defense date:
Examining board members:
Ligia Araujo Martini; Renata Bertazzi Levy; Barbara Santarosa Emo Peters
Advisor: Ligia Araujo Martini
Abstract

Introduction: Osteoporosis claims for strategies to preventing disease progression, ensuring a better quality of life to patients. Dietary patterns could provide information about the influence of overall diet on osteoporosis treatment, contributing to osteoporotic care. Objective: To investigate the association between dietary patterns and bone mineral density in postmenopausal women with osteoporosis. Methods: This cross-sectional study included 156 postmenopausal osteoporotic women, over 45 y, attended in an outpatient clinic in Sao Paulo, Brazil. Bone Mineral Density (BMD; g/cm2) of Lumbar Spine (LS), Total Femur (TF), Femoral Neck (FN), and Total Body (TB) were obtained by dual-energy X-ray absorptiometry. Weight (kg), height (m), Body Mass Index (BMI; kg/m2), body fat (g), lean mass (g) and lifestyle information were also assessed. Dietary intake was evaluated using a 3-day food diary. Dietary patterns were obtained by principal component factor in the 13 previously formed food groups. Adjusted linear regression analysis was applied in order to evaluate the predict effect of dietary patterns on BMD. Two-way ANOVA was used to investigate the association between dietary patterns and BMI with BMD, followed by a linear regression model stratified by BMI categories. Significance level was set as 5 per cent . Results: Five patterns were retained: 1) Healthy (vegetables, fruits, tubers, and tuberous roots); 2) Red meat and refined cereals; 3) Low-fat dairy; 4) Sweets, coffee and tea; and 5) Western (fats, snacks, pizzas, pies, soft drinks, and fruit drinks). The Sweets, coffee, and tea pattern was inversely associated with TF BMD ( = -0.178; CI 95 per cent : -0.039 - -0.000) and with TB BMD ( = -0.320; CI 95 per cent : -0.059 - -0.017), whereas the Healthy pattern was positively associated with TF BMD only among those who were in the normal BMI category ( = 0.251; CI 95 per cent : 0.002 0.056). Conclusions: A diet with higher intake of Sweets, coffee, and tea was a negatively associated with TF and TB BMD, whereas a Healthy pattern showed a positive association with TF BMD among the women with normal BMI. (AU)

FAPESP's process: 12/11702-3 - Association between dietary patterns and bone mineral density in adults
Grantee:Natasha Aparecida Grande de França
Support Opportunities: Scholarships in Brazil - Master