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Comparison between porcine acellular dermal matrix (Mucoderm®) versus connective tissue graft in the treatment of multiple adjacent gingival recessions associated with non-carious cervical lesion partially restored: randomized clinical trial

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Author(s):
Amanda Rossato
Total Authors: 1
Document type: Master's Dissertation
Press: São José dos Campos. 2020-01-30.
Institution: Universidade Estadual Paulista (Unesp). Instituto de Ciência e Tecnologia. São José dos Campos
Defense date:
Advisor: Mauro Pedrine Santamaria
Abstract

Clinical studies assessed different surgical-restorative treatment options to lead to single recessions associated with NCCL. However, although they are a common finding, insufficient evidence is available in the literature concerning about the treatment of multiple adjacent gingival recessions associated with non-carious cervical lesions and the optimal clinical protocol for the treatment of these lesions has not been established. Thus, the aim of this study was to compare two different multidisciplinary protocols by means of a randomized controlled clinical trial. For such purpose, forty patients with multiple adjacent gingival recessions associated with NCCL were enrolled and randomly allocated to one of the following groups: test group (n=20), partial restoration of cervical lesion and modified coronally advanced flap for root coverage associated with porcine acellular dermal matrix (MCAF+PR+XDM) and control group (n=20), partial restoration of cervical lesion and modified coronally advanced flap associated with connective tissue graft (MCAF+PR+CTG). After 6 months, CD coverage rates were 71,2% (2.5±1.1mm) for MCAF+PR+CTG and 59,7% (2±1.3mm) for MCAF+PR+XDM (p=0,1). MCAF+PR+CTG resulted in greater gain of keratinized tissue (p<0,05). MCAF+PR+XDM resulted in lower postoperative pain and shorter surgical time (p=0,001). Within the limitations of the present study, both groups resulted in esthetic improvements (p>0,05). MCAF +PR + CTG and MCAF+PR+XDM were effective to treat MCD, and the use of a xenogeneic dermal matrix is associated with lower postoperative pain and shorter chair time. (AU)

FAPESP's process: 18/03284-3 - Comparison between porcine acellular dermal matrix (Mucoderm®) versus connective tissue graft in the treatment of multiple gingival recessions associated with non-carious cervical lesion partially restored: randomized clinical trial
Grantee:Amanda Rossato
Support Opportunities: Scholarships in Brazil - Master