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Study of the viability of the piezoeletric poly(vinylidene fluoride) (PVDF) polymer application between cortical bone and osteosynthesis plate for growth bone simulation.

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Author(s):
André Luís Paschoal
Total Authors: 1
Document type: Doctoral Thesis
Press: São Carlos.
Institution: Universidade de São Paulo (USP). Instituto de Física de São Carlos (IFSC/BT)
Defense date:
Examining board members:
Lauralice de Campos Franceschini Canale; Aron Jose Pazin de Andrade; Vanderlei Salvador Bagnato; Alberto Cliquet Junior; Jose Baptista Portugal Paulin
Advisor: Lauralice de Campos Franceschini Canale
Abstract

The use of biomaterials to promote accelerated bone fracture repair has been improved in the recent years. In the present study, the piezoelectric properties of poly(vinylidene fluoride) were used with the aim of mimetizing bioelectrical potentials associated to bone strain which decrease when a bone fracture occurs. Histomorphometric studies were accomplished to verify the influence of the polymer. Biocompatibility and sterilization tests assessed any risk related to the use of a polymer as an implantable material. The piezoelectric polymer associated to an osteosynthesis plate resulted in a larger amount of mineralized bone matrix in the lesion when compared to a plate implanted without the polymer. (AU)