Longitudinal association between biological maturation, body fat and sports practice in predicting metabolic syndrome risk and c-reactive protein: structural equation models (abcd: growth study)

Author(s)

André Oliveira Werneck

• Document type: Master's Dissertation
• Press: Presidente Prudente. 2020-03-09.
• Institution: Universidade Estadual Paulista (Unesp). Faculdade de Ciências e Tecnologia. Presidente Prudente
• Defense date: 2020-02-26
• Advisor: Rômulo Araújo Fernandes

Abstract

The prospective association between biological maturation and metabolic syndrome risk still not clear. Moreover, there are potential mediators as physical activity practice and adiposity that can influence this association. Aim: Our aim was to analyze the association between somatic maturation and changes in metabolic syndrome (METs) risk and c-reactive protein (CRP), focusing on the effect of changes in trunk fat and sports practice, using a structural equation model Methods: This was an observational longitudinal study with a one-year follow-up. The sample was composed by 149 adolescents (49 without sports participation and 100 young athletes), aged between 10 and 17 years. As outcome, we adopted CRP components of METs, assessed through blood samples and using an electronic blood pressure equipment (triglycerides, HDL-c, fasting glucose and mean blood pressure). Somatic maturation was estimated using the Mirwald’s method. Structural equation models adjusted for sex, stature and chronological age were used for main analyses. Results: Somatic maturation was not associated with sports practice, trunk fat and METs risk. Sports practice was associated with a reduction in reduction in METs risk (β =-0.926;95%CI:-1.730, -0.130) as well as reduction in trunk fat (-9.154;-17.369, - 0.939), which was associated with increases in METs risk (0.018;0.004, 0.033). In the CRP model, somatic maturation was not associated with sports practice, trunk fat and CRP. However, sports practice was associated with a reduction in trunk fat (9.130;-17.345, -0.916), which in turn was associated with CRP reduction (0.006;0.001, 0.112). Conclusion: Sports practice was associated with reductions in trunk fat, METs risk and CRP through direct and indirect pathways. Trunk adiposity was directly associated with increases in METs risk and CRP. Sports practice should be stimulated aiming to prevent obesity and cardiovascular risk. (AU)

• FAPESP's process: 17/27234-2 - Longitudinal association between biological maturation, body fatness and sports participation predicting the risk of metabolic syndrome and C-reactive protein: structural equation modelling (ABCD - growth study)
• Grantee: André de Oliveira Werneck
• Support Opportunities: Scholarships in Brazil - Master