Analysis of behaviors of children during growth (ABCD - Growth Study)

• Grant number: 15/19710-3
• Support Opportunities: Regular Research Grants
• Duration: October 01, 2016 - September 30, 2018
• Field of knowledge: Health Sciences - Physical Education
• Principal Investigator: Rômulo Araújo Fernandes
• Grantee: Rômulo Araújo Fernandes
• Host Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil
• Associated researchers: Fábio Santos de Lira ; Han C G Kemper ; Manoel Carlos Spiguel Lima ; Manuel João Cerdeira Coelho e Silva
• Associated grant(s): 17/50026-7 - Impact of organized sports on health care costs of adolescents: ABCD Growth Study, AP.R SPRINT

Abstract

Objective: To identify the effect of behavioral variables on the pattern of metabolic, cardiovascular and inflammatory variables, as well as physical growth among adolescents. Methods: Cohort study with annual follow-up of over two years, which will start in 2016 in the city of Presidente Prudente. The sample size was previously calculated for all outcomes involved in the study and, thus, baseline measures of the cohort will involve at least 236 adolescents of both sexes aged between 11 and 14, which will be monitored in 2017 [12 months] and 2018 [24 months]). These adolescents will be recruited from public schools, private schools and sport clubs in the city. Annually will be assessed: risk behaviors (sleep behavior, smoking, alcohol consumption, habit of skipping meals and sedentary behavior), habitual physical activity, metabolic / inflammatory variables (lipid profile, insulin resistance and C-reactive protein), non-alcoholic fat liver disease, blood pressure, body fatness and biological maturation. Physical activity will be assessed through the use of accelerometer. Biological maturation will be assessed by the age at peak height velocity. In the statistical analysis, numeric variables (mean difference between the moments of analysis) will be expressed as mean, standard deviation and 95% confidence interval. Analysis of covariance will be used to compare the mean differences between physically active and inactive adolescents, under the adjustment of potential confounders. The adjustment of the multivariate models will be assessed by Levene's test and the Bonferroni test will be used when necessary. Effect size measures will be provided by Eta Squared values. Finally, the linear patterns of the variables throughout the follow-up will be related between them and expressed in beta values (²). The statistical significance will be set at in p-value <0.05. All statistical analyses will be performed in the software BioEstat (version 5.0). Expected Findings: It is expected to identify longitudinal changes in pattern of cardiovascular, metabolic and inflammatory variables during adolescence, as well as, to identify effects of behavioral variables on the longitudinal pattern of these variables. (AU)

Scientific publications

(11)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CAYRES-SANTOS, SUZIANE UNGARI; URBAN, JACQUELINE BEXIGA; BARBOSA, MAURICIO FREGONESI; LEMES, ITALO RIBEIRO; KEMPER, HAN C. G.; FERNANDES, ROMULO ARAUJO. Sports participation improves metabolic profile in adolescents: ABCD growth study. AMERICAN JOURNAL OF HUMAN BIOLOGY, v. 32, n. 5, SI, DEC 2019. (15/04961-0, 15/19710-3)

LYNCH, KYLE R.; ANOKYE, NANA K.; VLACHOPOULOS, DIMITRIS; BARBIERI, FABIO A.; TURI-LYNCH, BRUNA C.; CODOGNO, JAMILE S.; AGOSTINETE, RICARDO R.; FERNANDES, ROMULO A.. Impact of sports participation on incidence of bone traumatic fractures and health-care costs among adolescents: ABCD - Growth Study. PHYSICIAN AND SPORTSMEDICINE, NOV 2019. (17/09182-5, 15/19710-3, 16/20377-0)

TORRES, WESLEY; CAYRES-SANTOS, SUZIANE UNGARI; URBAN, JACQUELINE BEXIGA; DE MORAES-CHAGAS, LUCAS GABRIEL; CHRISTOFARO, DIEGO GIULLIANO DESTRO; TURI-LYNCH, BRUNA CAMILO; CODOGNO, JAMILE SANCHES; FERNANDES, ROMULO ARAUJO. Participation in Non-professional Sports and Cardiovascular Outcomes Among Adolescents: ABCD Growth Study. MATERNAL AND CHILD HEALTH JOURNAL, v. 24, n. 6, APR 2020. (15/19710-3, 18/09131-4)

AGOSTINETE, RICARDO R.; WERNECK, ANDRE O.; MAILLANE-VANEGAS, SANTIAGO; GRACIA-MARCO, LUIS; UBAGO-GUISADO, ESTHER; CONSTABLE, ANNIE M.; FERNANDES, ROMULO A.; VLACHOPOULOS, DIMITRIS. The Mediating Role of Lean Soft Tissue in the Relationship between Somatic Maturation and Bone Density in Adolescent Practitioners and Non-Practitioners of Sports. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, v. 18, n. 6, MAR 2021. (17/09182-5, 16/20354-0, 16/06920-2, 18/24164-6, 13/06963-5, 15/13543-8, 15/19710-3, 17/27234-2)

WERNECK, ANDRE OLIVEIRA; AGOSTINETE, RICARDO RIBEIRO; CAYRES, SUZIANE UNGARI; URBAN, JACQUELINE BEXIGA; WIGNA, ANDREA; DE MORAES CHAGAS, LUCAS GABRIEL; TORRES, WESLEY; FERNANDES, ROMULO ARAUJO. Association between Cluster of Lifestyle Behaviors and HOMA-IR among Adolescents: ABCD Growth Study. MEDICINA-LITHUANIA, v. 54, n. 6, DEC 2018. (15/04961-0, 17/09182-5, 15/19710-3, 17/27234-2)

WERNECK, ANDRE O.; RONQUE, V, ENIO R.; FERNANDES, ROMULO A.. Structural equation model of the effect of biological maturation on metabolic syndrome risk and C-reactive protein: effect of trunk fat and sports participation. SCIENTIFIC REPORTS, v. 11, n. 1, SEP 10 2021. (15/19710-3, 18/22593-7, 17/27234-2)

LUIZ-DE-MARCO, RAFAEL; KEMPER, HAN; AGOSTINETE, RICARDO RIBEIRO; WERNECK, ANDRE OLIVEIRA; MAILLANE-VANEGAS, SANTIAGO; FAUSTINO-DA-SILVA, YURI DA SILVA; EXUPERIO, ISABELLA; FERNANDES, ROMULO ARAUJO. Sports participation and muscle mass affect sex-related differences in bone mineral density between male and female adolescents: A longitudinal study. São Paulo Medical Journal, v. 137, n. 1, p. 75-81, JAN-FEB 2019. (17/13003-9, 16/20354-0, 17/09182-5, 15/19710-3, 17/27234-2, 16/20377-0)

CAYRES, SUZIANE UNGARI; WERNECK, ANDRE OLIVEIRA; URBAN, JACQUELINE BEXIGA; TURI-LYNCH, BRUNA CAMILO; BARBOSA, MAURICIO FREGONESI; FERNANDES, ROMULO ARAUJO. Sports participation is inversely associated with C-reactive protein levels in adolescents: ABCD Growth Study. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, v. 29, n. 7, p. 1000-1005, JUL 2019. (15/04961-0, 15/19710-3, 17/27234-2)

AGOSTINETE, RICARDO RIBEIRO; FERNANDES, ROMULO ARAUJO; NARCISO, PEDRO HENRIQUE; MAILLANE-VANEGAS, SANTIAGO; WERNECK, ANDRE OLIVEIRA; VLACHOPOULOS, DIMITRIS. Categorizing 10 Sports According to Bone and Soft Tissue Profiles in Adolescents. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, v. 52, n. 12, p. 2673-2681, DEC 2020. (16/20354-0, 13/06963-5, 18/24164-6, 17/09182-5, 15/19710-3, 17/27234-2, 16/06920-2, 18/21935-1)

NARCISO, PEDRO HENRIQUE; WERNECK, ANDRE OLIVEIRA; LUIZ-DE-MARCO, RAFAEL; VENTURA FAUSTINO-DA-SILVA, YURI DA SILVA; MAILLANE-VANEGAS, SANTIAGO; AGOSTINETE, RICARDO RIBEIRO; FERNANDES, ROMULO ARAUJO. Influential role of lean soft tissue in the association between training volume and bone mineral density among male adolescent practitioners of impact-loading sports: ABCD Growth study. BMC PEDIATRICS, v. 20, n. 1, OCT 28 2020. (15/19710-3, 18/21935-1)

LUIZ-DE-MARCO, RAFAEL; GOBBO, LUIS ALBERTO; CASTOLDI, ROBSON CHACON; MAILLANE-VANEGAS, SANTIAGO; DA SILVA VENTURA FAUSTINO-DA-SILVA, YURI; EXUPERIO, ISABELA NETO; AGOSTINETE, RICARDO RIBEIRO; FERNANDES, ROMULO A.. Impact of changes in fat mass and lean soft tissue on bone mineral density accrual in adolescents engaged in different sports: ABCD Growth Study. ARCHIVES OF OSTEOPOROSIS, v. 15, n. 1, FEB 23 2020. (17/09182-5, 17/13003-9, 15/19710-3, 16/20377-0, 16/20354-0)