CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Biomedicine from Universidade Estadual Paulista Júlio de Mesquita Filho (1996), M.Sc. (1999) and Ph.D. in Psychobiology from Universidade Federal de São Paulo (2004) and Postdoctoral from Emory University (2010). In 2010, she was invited to be a Visiting Associate Professor at the Division of Neuropharmacology and Neurologic Disease (Yerkes National Primate Research Center, Emory University). In 2012, was invited to be Visiting Professor at Harvard Medical School (New England Primate Research Center). Currently, Associate Professor and head of the Sleep Division at Universidade Federal de São Paulo, Director of the of Sleep Institute/São Paulo and Editor-in-Chief of Sleep Medicine Reviews. Published over 730 papers in international scientific journals, and author of 8 books and more than 60 chapters. She has experience in Psychobiology and works on the following topics: sleep deprivation, endocrine regulation, sexual behavior and its interface with sleep and microbiota, skin/dermatology, neurobiology of drug abuse and pain mechanisms. In 2007, she was awarded in the Women in Science Program by LOreal/Brazilian Academy of Sciences and UNESCO. In 2025, she was listed as one of the 2 percent most relevant researchers in the world by the University of Stanford, both considering her entire career and her research output and impact in 2024. (Source: Lattes Curriculum)
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Poor sleep quality is closely linked to comorbidities in several organic systems. Among sleep disorders, there has been a recent increase in the prevalence of obstructive sleep apnea (OSA) in the population, especially in men. The intermittent hypoxia resulting from OSA can produce physiopathological symptoms, including the impairment of reproductive function, especially in relation to er…
To assess the trilateral relationship between obstructive sleep apnea (OSA), erectile dysfunction (ED) and male fertility potential. Method: With this goal, the project proposes 5 sub-studies. Seventy-one men between 18 and 60 years old will be recruited for each of the 4 groups, resulting in 284 volunteers total, being the groups: 1) Without OSA and without ED; 2) With OSA and without ED…
Leishmania is the protozoan responsible for leishmaniasis, a neglected disease that in Brazil causes about 100,000 new cases per year. In its life cycle, the parasite is found in the midgut of an insect or inside the phagolysosome in the macrophage of the mammalian host. The different stages of parasite life cycle influence the regulation of gene expression, which occurs at post-transcrip…
(Only some records are available in English at this moment)
Psoriasis is a chronic inflammatory disease that affects the skin and impacts approximately 2 to 3% of the global population. Although it is a dermatological condition, it has systemic repercussions and associated clinical comorbidities. Obstructive sleep apnea (OSA), inturn, is a common sleep disorder that affects, on average, one-third of the population, particularlyobese men. It is cha…
Sleep restriction produces several undesirable effects on the body, such as an increase in body mass index (BMI) due to reduced impulsive control over high-calorie and nutrient-poor foods. These foods contribute to low serum levels of magnesium and zinc. Studies indicate a relationship between these minerals and impulsivity, that is, decision-making without critical thinking. This project…
Poor sleep quality is closely linked to comorbidities in several organic systems. Among sleep disorders, there has been a recent increase in the prevalence of obstructive sleep apnea (OSA) in the population, especially in men. The intermittent hypoxia resulting from OSA can produce physiopathological symptoms, including the impairment of reproductive function, especially in relation to er…
Introduction: Obstructive sleep apnea (OSA) is a condition characterized by the partial or complete obstruction of the upper airway during sleep, resulting in sleep fragmentation and intermittent hypoxemia. The global prevalence of OSA is alarming, affecting approximately 1 billion individuals. Epidemiological studies have shown an association between sleep disorders, such as OSA, and chr…
Change in sleep pattern is a condition with implications for public health. Studies have shownthat the intestinal microbiota has a constant and bidirectional connection with the brainthrough the brain-gut-microbiota axis, which is related to the tryptophan pathways, aprecursor of serotonin and, consequently, melatonin (sleep-regulating hormone).Inflammatory bowel diseases (IBD), whose pre…
(Only some records are available in English at this moment)
The first experiments that demonstrated the importance of the balance between T helper 1 (Th1) and T helper 2 (Th2) were conducted in experimental models of murine leishmaniasis. After the inoculation of a higher number of Leishmania major parasites, some mice strains proved to be resistant, as observed in C57BL/6 strain, and others develop lesions and even systemic disease, as in BALB/c …
Drug addiction is a chronic relapsing disorder which currently represents a global public health concern. Despite decades of research, there is no cure for drug abuse to date, mainly due to the heterogeneity of this disease and all the factors influencing it. Among them, one of the major clinical complaints reported by drug users is sleep impairment, which per se can worsen the course of …
We will explore the hypothesis that sleep loss induces cellular damage, leading to up-regulation of inflammatory markers, down-regulation of lipid transport pathways and up-regulation of fatty acid and triglyceride synthesis, favoring cardiometabolic diseases. Pharmacological approach will be used to investigate the role of the NLRP3 and LXR activation and inactivation on the inflammatory…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 8 / 6 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 41 / 35 | Completed scholarships in Brazil |
| 4 / 4 | Completed scholarships abroad |
| 56 / 48 | All research grants and scholarships |
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