CV Lattes
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ORCID
Universidade Federal do ABC (UFABC). Centro de Ciências Naturais e Humanas (CCNH) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Bacharel Em Química from Universidade de São Paulo Faculdade de Filosofia Ciências e Letras de Ribei (1998), master's at Chemistry from Universidade Estadual de Campinas (2001) and ph.d. at Chemistry from Universidade Estadual de Campinas (2006). Has experience in Chemistry, acting on the following subjects: nitric oxide donors, biomaterials, nitric oxide, óxido nítrico and peo-ppo-peo copolymer. (Source: Lattes Curriculum)
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Cardiovascular disease (CVD) is a global health crisis, causing nearly 18 million deaths annually. Despite medical advancements, effective treatments to restore vascular function and prevent heart damage are still lacking. Gasotransmitters like nitric oxide (NO) and hydrogen sulfide (H¿S) play vital roles in cardiovascular health, regulating vasodilation, inflammation, and tissue repair. …
The gaseous transmitters nitric oxide (NO) and hydrogen sulfide (H2S) are endogenous molecules of great relevance in several physiological and pathophysiological processes. Both molecules, depending on their concentrations and the cellular environment where they are found, can have anti-inflammatory, antioxidant, pro-apoptotic, cytoprotective and antimicrobial actions. Importantly, these …
Acute and chronic coronary artery diseases are leading causes of deaths worldwide, demanding new advanced healthcare strategies to mitigate this risk, including the development of materials and inter/trans-disciplinary approaches to treat coronary artery occlusion or stenosis. Hence, the main aim of this project is the development of new polymeric biomaterials for applications in the fiel…
The free radical nitric oxide (NO) plays important actions in several biological processes in mammals, such as the control of vasodilation, immune response, cellular communication and skin healing. NO is also recognized as a key molecule in several physiological processes in plants, including dormancy breaking and seed germination, root growth, flowering, regulation of pollen tube growth,…
Nanotechnology has the potential to make an impact in agriculture through nanoencapsulation of pesticides, herbicides and agrochemicals resulting in precise dosage to the plants. Silver and copper nanoparticles are known to have potent antimicrobial activity against several pathogens. Although these nanoparticles have been greatly explored in biomedical applications, their uses in plant d…
(Only some records are available in English at this moment)
Gasotransmitters are bioactive molecules that act as endogenous signaling agents. Among the three major gasotransmitters, nitric oxide (NO) and hydrogen sulfide (H¿S) stand out due to their involvement in diverse physiological and pathophysiological processes. Depending on their concentration and cellular environment, both molecules can exhibit anti-inflammatory, antioxidant, pro-apoptoti…
O alginato é um biopolímero extraído de espécies de algas castanhas, que tem sido amplamente utilizado como hidrogel em aplicações farmacêuticas e biomédicas devido à sua biocompatibilidade, biodegradabilidade, baixo custo, mucoadesividade e elevada capacidade de associar e libertar moléculas terapêuticas. Nanopartículas poliméricas são eficazes na entrega de fármacos para células-alvo e …
Nitric oxide (NO) and hydrogen sulfide (H2S) are endogenous molecules and gaseous transmitters of great relevance in several physiological and pathophysiological processes. Both molecules, depending on their concentrations and the cellular environment where they are found, can have anti-inflammatory, antioxidant, pro-apoptotic, cytoprotective and antimicrobial actions. Recent studies sugg…
Nitric oxide (NO), an endogenous free radical, plays a crucial role in controlling biological processes, such as vasodilation, tissue regeneration and repair, apoptosis and immune defense. Its application in regenerative and antitumor therapies stands out as promising for stimulating tissue regeneration and promoting anticancer responses. In this project, it is proposed to develop nanopar…
Nanotechnology has been drawing the attention of the scientific community due to the properties that these nanomaterials have. Nanoparticles based on metals and metalloids, especially zinc oxide (ZnO NPs) and selenium (Se NPs) nanoparticles, are prominent in the biomedical and, more recently, agricultural areas, as they have potent antimicrobial and antitumor properties. The use of nanopa…
(Only some records are available in English at this moment)
Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide, driven by endothelial dysfunction, mitochondrial impairment, and inflammation. Nitric oxide (NO) and hydrogen sulfide (H¿S) are key endogenous gasotransmitters that modulate vasodilation, oxidative stress, and cellular bioenergetics. However, current delivery systems for NO and H¿S suffer from short release durat…
Bone regeneration remains a challenge in orthopedic and maxillofacial applications, particularly in large defects that exceed the body's natural healing capacity. In this sense, 3D-printed calcium-deficient hydroxyapatite scaffolds, developed by Prof. Maria-Pau Ginebra's group, provide a highly osteoconductive platform with excellent structural properties, presenting an opportunity for fu…
Hepatocellular carcinoma (HCC) is the third death cause in cancer with low survival rate and resistance to conventional chemotherapy, specially at intermediate and advanced stages. In this sense, nanomedicine has demonstrated as a promising strategy for overcoming chemoresistance and proportionate reduced side effects. Silica oxide nanoparticles (SiO2 NPs) and ZnO NPs have been reported a…
Neisseria gonorrhoeae is an obligate human bacterium responsible for causing gonorrhea. It infects the mucosal epithelium of the male urethra and female endo/ectocervix, causing more than 87 million cases per year. Although antibiotics have been successful for treating gonococcal infections, N. gonorrhoeae has developed multidrug resistance, being among the most multidrug-resistant bacter…
Recently, hybrid nanoparticles composed of noble metals and superparamagnetic nanoparticles have attracted the attention of the scientific community due to the versatility of nanomaterials with different characteristics and functions in a single nanostructure. The combination of superparamagnetic iron oxide nanoparticles (Fe3O4 NPs) with silver nanoparticles (AgNPs) leads to hybrid Fe3O4@…