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Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Aplicadas (FCA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Mariana Portovedo de Oliveira Araújo in research grants and scholarships supported by FAPESP.
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Obesity is nowadays a problem of public health worldwide and is determined by the accumulation of body fat mass. This fact is given by the loss of energy homeostasis, and the hypothalamus is the region of the brain responsible for coordinating food intake and energy expenditure by signaling peripheral hormones. It is known that this region suffers an inflammatory process during the develo…
Obesity and type 2 diabetes are associated with activation of signaling pathways and increased inflammatory cytokine production. In turn, hypothalamic inflammation is associated with a lack of control of mechanisms of hunger and thermogenesis and consequently, with the development of obesity. Long chain saturated fatty acids leads to the activation of TLR4 signaling, ER stress and resista…
The mediobasal hypothalamus is the primary site responsible for the balance between food intake and energy expenditure, and disruption in these neurons can contribute to the development of obesity. In experimental models, obesity is known to be associated to a low grade inflammation that appears first in the hypothalamus. In this context, the high content of saturated fatty acids in the…
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 3 / 3 | All Scholarships |
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