CV Lattes
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Universidade de São Paulo (USP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
He earned his Bachelors degree in Chemistry from the Institute of Chemistry at the University of São Paulo (USP) in 1992 and completed his Ph.D. in Organic Chemistry in 1997 under the supervision of Prof. Dr. Josef Wilhelm Baader, with a dissertation titled Mechanistic Study of the Peroxyoxalate System. He then conducted postdoctoral research at the same institute, this time in the Department of Biochemistry, working within the research group led by Prof. Dr. Etelvino José Henriques Bechara. He is currently an Associate Professor, teaching courses in Environmental and Organic Chemistry at the University of São Paulo, where he leads research on fungal bioluminescence. His expertise includes bioluminescence, biochemistry, chemiluminescence, metagenomics, and organic chemistry. Internationally recognized in his field, Stevani has made pioneering contributions to unraveling the chemical mechanisms behind fungal light emission, including the discovery of the Caffeic Acid Cycleessential for bioluminescence in certain fungal species. His research has significantly deepened scientific understanding of natural light-emitting systems and their potential biotechnological applications, such as in bioimaging, biosensors, and synthetic biology. In addition to his scientific work, he is also deeply committed to teaching and mentoring both undergraduate and graduate students in the areas of chemistry, photochemistry, and molecular biology. His laboratory is widely recognized for its multidisciplinary approach, integrating chemical, biochemical, and photophysical methods to investigate bioluminescent systems in a range of organisms, including fungi, dipterans, marine species, and millipedes. (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| Natural lighting |
| Iluminación natural |
| Luces vivas |
| Living lights |
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| News published in Agência FAPESP Newsletter about the researcher |
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| Articles published in other media outlets ( ): |
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Sunlight is vital for life, yet its involvement in metabolic processes comes at a cost. When biomolecules absorb solar radiation, they become electronically excited, increasing their propensity for electron and energy transfer. This can lead to: (i) the production of reactive species that may be either beneficial or harmful, depending on their nature, quantity, and location, and (ii) evol…
Bioluminescence (BL) is an important indicator of aerobic life, having served as a model for multidisciplinary studies, bringing important scientific discoveries, providing valuable bioanalytical tools and luminescent indicators. BL has the potential to meet the growing demands for increasingly faster, more sensitive and practical tests imposed by the current climate and environmental cri…
HELVA (Hybrid ELectrosynthesis of Value-Added chemicals) seeks to demonstrate a hybrid system that integrates the synthesis complex carbon-based molecules through tandem carbon dioxide electroreduction into acetate and microbial upgrade into polyhydroxyalkanoate (PHA). The project starts at a TRL = 2 and is projected to end at a TRL of 4. (AU)
A Luminescência é um tema multidisciplinar com amplas aplicações em diversos campos, impulsionando avanços científicos e tecnológicos. Destacam-se a bioluminescência e a quimiluminescência, originadas de reações químicas e organismos vivos, com relevância em química, biologia e aplicações analíticas. A International Society of Bioluminescence and Chemiluminescence (ISBC), desde 1991, prom…
Light, molecular oxygen, and free radicals are the essence of life... for the good and the evil. They provide energy and matter for living beings, but charge a high price - diseases, ageing, death -, via electron-transfer reactions and electronic photo- and chemiexcitation of molecules. Our project concerns these processes through the study of the molecular nature of living lights (biolum…
O projeto tem como metas: a) a produção de saxitoxinas para o desenvolvimento de ensaios analíticos, bem como para ser utilizada como padrão analítico, em amostras de água e de florações; b) a implementação de ensaio-padrão para sua determinação, utilizando a separação por HPLC e detecção por oxidação pós-coluna, c) o desenvolvimento de um aptasensor, baseado em um aptâmero, marcado ou nã…
(Only some records are available in English at this moment)
The cyanobacterium Synechocystis sp. PCC6803 has emerged as an efficient producer of a special derivative of polyhydroxyalkanoates (PHA), poly(3-hydroxybutyrate) (PHB). This remarkable property holds significant potential for biotechnological applications, particularly in the realm of directly deriving PHB from CO2 and CO2-derived acetate, which will be obtained from the Hybrid Electrosyn…
Basidiomycete bioluminescence and the ascomycete biological clock system have been described in the literature. With this project, we want to understand the regulation of basidiomycete bioluminescence and develop biotechnological applications. Initially, a N. gardneri genetic transformation protocol will be implemented and later on, the cultivation of mutant N. gardneri strains for clock …
Bioluminescence can be defined as the process of emission of cold and visible light by living organisms, which is present in a wide variety of marine animals. Several of these luminescent systems have been investigated in recent decades, producing broad, basic and applied knowledge. However, many bioluminescent systems have not been researched sufficiently and are even unknown, such as th…
The caffeic acid cycle (CAC) is the metabolic pathway that promotes the biosynthesis and recycling of the fungal luciferin, 3-hydroxyhispidin, which is the luciferase substrate resulting in light emission. Fungal luciferin is produced from the hydroxylation of hispidin in a reaction catalyzed by hispidin-3-hydroxylase (H3H). In reproductive structures of certain plants is produced the gly…
(Only some records are available in English at this moment)
The cyanobacterium Synechocystis sp. B12, initially isolated from the mangrove habitat of Brazil, has emerged as a proficient producer of a specialized derivative of polyhydroxyalkanoates (PHA), specifically poly(3-hydroxybutyrate) (PHB), exhibiting an impressive yield of 31% cell dry weight (cdw) under light intensity of 300 ¼mol photons/m2s1. This distinctive characteristic presents sub…
The manipulation of microbial genetics has become an essential tool for the study of pathogenicity and host-pathogen interactions, with the ascomycete's phylum playing host to a diverse range of pathogenic fungi that cause a significant impact on society, including those that parasitize humans and crops. Plant transformation through the introduction of the fungal bioluminescence pathway, …
Due to the restrictions imposed by the COVID-19 pandemic situation, several bioluminescent fungi collected at Atlantic Rainforest (Brazil) by our group over the last three years remain waiting taxonomic classification. Besides morphological analysis, DNA sequencing and phylogenetic analysis of combined barcodes are crucial for fungal systematics and evolution studies. Thus, the first aim …