CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Associate Professor at the State University of Campinas (UNICAMP) since 2010. She served as a Professor in the Nutrition course at FCA until 2023. As of 2024, she works as a Professor at the Institute of Biology (IB) in the Structural and Functional Biology Department at UNICAMP. She held 3 Post-Doctorates, one in Brazil at Faculdade de Ciências Médicas (FCM) at UNICAMP (2002 to 2006). Two of them abroad, in the Division of Endocrinology, Diabetes and Metabolism of Beth Israel Deaconess Medical Center (BIDMC) at Harvard Medical School, in Boston, USA (2006 to 2009); in 2021 at the Max Planck Institute for Metabolism Research, Cologne, Germany. Nowadays, she is dedicated to understanding the molecular mechanisms involved in the dysregulation of food intake and energy metabolism in animal models subjected to air pollution and diets with ultra-processed foods. Recently, she began studies in the field of psychedelics, investigating the effects of ayahuasca and DMT on the feeding behavior of rodents. (Source: Lattes Curriculum)
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The worldwide prevalence of individuals with obesity has doubled since 1990, and in 2022, more than 1 billion people worldwide were overweight. Body fat accumulation is associated with higher mortality rates and the development of comorbidities. Air pollution, represented by particulate matter 2.5 (PM2.5), and ultra-processed foods (UPF) have been recognized as drivers of the obesity epid…
A previous study demonstrated that a high-fat diet (HFD), administered for one-three-days, induces hypothalamic inflammation before obesity's established, and the long term affects leptin signaling/action due to inflammation. We investigate whether exposure to particulate matter of a diameter of less than 2.5 um (PM2.5) in mice fed a chow diet leads to similar metabolic effects caused by …
Obesity has been exponentially increasing in the last decades, making urgent to understand the underlying mechanisms contributing to its development, maintenance and associated comorbidities. The maintenance of energetic homeostasis is under the control of endocrine hormones and neural signals. The hormones, insulin and leptin, are the most investigated in central energy regulation, as we…
Exposure to air pollution has been highlighted as an important risk factor for morbidity and mortality in the world. Several pollutants, such as particulate matter weighing d 2.5 ¼m (MP2.5), as well as one of its chemical compounds, 1,2-naphthoquinone (1,2-NQ), obtained by burning diesel, have been associated with the genesis of chronic diseases, including type 2 diabetes mellitus (T2D). …
(Only some records are available in English at this moment)
Obesity and its comorbidities, such as Type 2 Diabetes Mellitus, have increased exponentially, making it urgent to understand the mechanisms involved in the development of these diseases. The maintenance of energy homeostasis is performed by hormones such as leptin and insulin in addition to neural signs. Our group recently demonstrated that Clk2 (Cdc-like kinase 2) is expressed in hypoth…
Long-term exposure to air pollution may have unfavorable effects on health. Particulate matter (PM) diameter less than or equal to 2.5 µm (PM2.5) is associated with the induction of chronic inflammation. Obesity may be a consequence of the imbalance between food consumption and energy expenditure. JAK2 / STAT3 pathway in hypothalamic nuclei is an important hallmark of leptin signaling and…
Exposure to air pollution has been highlighted as an important risk factor for morbidity and mortality in the world. Several pollutants, such as particulate matter with diameter d 2.5 ¼m (MP2.5), as well as one of its chemical compounds, 1,2-naphthoquinone (1,2-NQ), obtained by burning diesel, have been associated with the genesis of chronic diseases, including type 2 diabetes mellitus (T…
(Only some records are available in English at this moment)
The capacity to adjust food intake in response to changing energy requirements is essential for survival and the hypothalamus plays an important role in the regulation of whole-body energy balance by integrating nutrient and hormone signals from peripheral inputs. Insulin and leptin are hormones that though their intracellular signaling control food intake and energy expenditure stimulati…