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Patrícia de Oliveira Prada

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Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Aplicadas (FCA)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

She was graduated in Nutrition from the University of the State of Rio de Janeiro (UERJ). She did a Specialization in Nutrition Area at Santa Casa de Misericórdia in Rio de Janeiro and a Residency in Nutrition at Pedro Ernesto University Hospital (Rio de Janeiro). She holds a Ph.D. in Science from the University of São Paulo (USP). She was a postdoctoral fellowship in the clinical research laboratory in insulin resistance at the School of Medical Sciences of UNICAMP from 2002 to 2006 and a postdoctoral fellowship at the Division of Endocrinology, Diabetes, and Metabolism at Beth Israel Deaconess Medical Center (BIDMC)/Harvard Medical School in Boston from 2006 to 2009. She is currently Professor of Nutrition at the School of Applied Sciences (FCA) of UNICAMP at the Campus of Limeira, São Paulo, where she coordinates the Laboratory of Molecular Research in Obesity (LabIMO). Her research line is about the identification and understanding of the physiological, pathophysiological, and molecular mechanisms that control food intake. In this line, she has international publications that have identified signaling proteins in the hypothalamus and reward system that participate in the control of food intake, contributing to the genesis of obesity. She has international publications demonstrating the importance of the gut microbiota in the regulation of body weight and food intake. Also, she has ongoing research projects that investigate possible pathophysiological and molecular mechanisms involved in the management of food intake in the face of environmental challenges, such as consumption of very palatable diets (cafeteria diet) and exposure to air pollution. (Source: Lattes Curriculum)

Research grants
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FAPESP support in numbers * Updated November 09, 2019
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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (13)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Data from Web of Science

ZECCHIN, H. G.; GASPARETTI, A. L.; TORSONI, M. A.; UENO, M.; HIRATA, A. E.; AMARAL, M. E. C. DO; HÖER, N. F.; BOSCHERO, A. C.; SAAD, M. J. A.; PRADA, P. DE O.. Western diet modulates insulin signaling, c-jun n-terminal kinase activity, and insulin receptor substrate-1ser307 phosphorylation in a tissue-specific fashion. Endocrinology, v. 146, n. 3, p. 1576-1587, .

PRADA‚ P.O.; OKAMOTO‚ M.M.; FURUKAWA‚ L.N.S.; MACHADO‚ U.F.; HEIMANN‚ J.C.; DOLNIKOFF‚ M.S.. High-or low-salt diet from weaning to adulthood: effect on insulin sensitivity in Wistar rats. Hypertension, v. 35, n. 1, p. 424-429, .

CONDES AREIAS, MARIA FERNANDA; PRADA, PATRICIA OLIVEIRA. Mechanisms of insulin resistance in the amygdala: Influences on food intake. Behavioural Brain Research, v. 282, p. 209-217, . Web of Science Citations: 23. (12/10338-6, 13/07607-8)

WEISSMANN, LAIS; QUARESMA, PAULA G. F.; SANTOS, ANDRESSA C.; DE MATOS, ALEXANDRE H. B.; PASCOAL, VINICIUS D'AVILA BITTENCOURT; ZANOTTO, TAMIRES M.; CASTRO, GISELE; GUADAGNINI, DIOZE; DA SILVA, JOELCIMAR MARTINS; VELLOSO, LICIO A.; et al. IKK epsilon Is Key to Induction of Insulin Resistance in the Hypothalamus, and Its Inhibition Reverses Obesity. Diabetes, v. 63, n. 10, p. 3334-3345, . Web of Science Citations: 20. (12/10338-6, 13/07607-8, 10/52068-0)

CASTRO, GISELE; AREIAS, MARIA FERNANDA C.; WEISSMANN, LAIS; QUARESMA, PAULA G. F.; KATASHIMA, CARLOS K.; SAAD, MARIO J. A.; PRADA, PATRICIA O.. Diet-induced obesity induces endoplasmic reticulum stress and insulin resistance in the amygdala of rats. FEBS OPEN BIO, v. 3, p. 443-449, . Web of Science Citations: 37.

PRADA, PATRICIA O.; QUARESMA, PAULA G. F.; CARICILLI, ANDREA M.; SANTOS, ANDRESSA C.; GUADAGNINI, DIOZE; MORARI, JOSEANE; WEISSMANN, LAIS; ROPELLE, EDUARDO R.; CARVALHEIRA, JOSE BARRETO C.; VELLOSO, LICIO A.; et al. RETRACTED: Tub Has a Key Role in Insulin and Leptin Signaling and Action In Vivo in Hypothalamic Nuclei(Retracted article. See vol. 66, pg. 785, 2017). Diabetes, v. 62, n. 1, p. 137-148, . Web of Science Citations: 24.

QUARESMA, P. G. F.; REENCOBER, N.; ZANOTTO, T. M.; SANTOS, A. C.; WEISSMANN, L.; DE MATOS, A. H. B.; LOPES-CENDES, I.; FOLLI, F.; SAAD, M. J. A.; PRADA, P. O.. Pioglitazone treatment increases food intake and decreases energy expenditure partially via hypothalamic adiponectin/adipoR1/AMPK pathway. International Journal of Obesity, v. 40, n. 1, p. 138-146, . Web of Science Citations: 11. (12/10338-6, 13/07607-8)

PRADA, PATRICIA O.; SAAD, MARIO J. A.. Tyrosine kinase inhibitors as novel drugs for the treatment of diabetes. EXPERT OPINION ON INVESTIGATIONAL DRUGS, v. 22, n. 6, p. 751-763, . Web of Science Citations: 1. (12/10338-6)

QUARESMA, P. G. F.; WEISSMANN, L.; ZANOTTO, T. M.; SANTOS, A. C.; DE MATOS, A. H. B.; FURIGO, I. C.; SIMABUCO, F. M.; DONATO, JR., J.; BITTENCOURT, J. C.; LOPES-CENDES, I.; et al. Cdc2-like kinase 2 in the hypothalamus is necessary to maintain energy homeostasis. International Journal of Obesity, v. 41, n. 2, p. 268-278, . Web of Science Citations: 4. (12/10338-6, 13/07607-8, 15/00343-0)

CARICILLI, ANDREA M.; PENTEADO, ERICA; DE ABREU, LELIA L.; QUARESMA, PAULA G. F.; SANTOS, ANDRESSA C.; GUADAGNINI, DIOZE; RAZOLLI, DANIELLA; MITTESTAINER, FRANCINE C.; CARVALHEIRA, JOSE B.; VELLOSO, LICIO A.; et al. Topiramate Treatment Improves Hypothalamic Insulin and Leptin Signaling and Action and Reduces Obesity in Mice. Endocrinology, v. 153, n. 9, p. 4401-4411, . Web of Science Citations: 25.

MENDES, NATALIA FERREIRA; CASTRO, GISELE; GUADAGNINI, DIOZE; TOBAR, NATALIA; COGNUCK, SUSANA QUIROS; KAGOHARA ELIAS, LUCILA LEICO; BOER, PATRICIA ALINE; PRADA, PATRICIA OLIVEIRA. Knocking down amygdalar PTP1B in diet-induced obese rats improves insulin signaling/action, decreases adiposity and may alter anxiety behavior. METABOLISM-CLINICAL AND EXPERIMENTAL, v. 70, p. 1-11, . Web of Science Citations: 7. (13/07607-8, 15/00343-0)

ZAMBOM DE SOUZA, ALESSANDRA ZANIN; ZAMBOM, ADRIANO ZANIN; ABBOUD, KAHLILE YOUSSEF; REIS, SABRINA KAREN; TANNIHAO, FABIANA; GUADAGNINI, DIOZE; SAAD, MARIO J. A.; PRADA, PATRICIA OLIVEIRA. Oral supplementation with L-glutamine alters gut microbiota of obese and overweight adults: A pilot study. NUTRITION, v. 31, n. 6, p. 884-889, . Web of Science Citations: 19. (12/10338-6, 13/07607-8)

ABBOUD, KAHLILE YOUSSEF; REIS, SABRINA KAREN; MARTELLI, MARIA EDUARDA; ZORDAO, OLIVIA PIZETTA; TANNIHAO, FABIANA; DE SOUZA, ALESSANDRA ZANIN ZAMBOM; ASSALIN, HELOISA BALAN; GUADAGNINI, DIOZE; ROCHA, GUILHERME ZWEIG; SAAD, MARIO JOSE ABDALLA; et al. Oral Glutamine Supplementation Reduces Obesity, Pro-Inflammatory Markers, and Improves Insulin Sensitivity in DIO Wistar Rats and Reduces Waist Circumference in Overweight and Obese Humans. NUTRIENTS, v. 11, n. 3, . Web of Science Citations: 0. (17/18498-6)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)


CASTRO, Gisele de. Obesidade induzida por dieta desencadeia estresse do retículo endoplasmático e resistência à insulina em amígdala de ratos. 2013. Dissertação (Mestrado) - Faculdade de Ciências Aplicadas. Universidade Estadual de Campinas (UNICAMP). (11/15013-5)

CASTRO, Gisele de. A regulação da proteína quinase ativada pelo AMP (AMPK) no CeA e os efeitos sobre o controle da ingestão alimentar e gasto energético. 2017. Tese (Doutorado) – Universidade Estadual de Campinas, Faculdade de Ciências Médicas. (14/16724-0)

WEISSMANN, Laís. A serina quinase IKK epsilon (IKKe) é importante para a ação e sinalização da insulina e leptina no hipotálamo de camundongos obesos. 2013. Dissertação (Mestrado) - Faculdade de Ciências Médicas. Universidade Estadual de Campinas (UNICAMP). (11/02289-2)

AREIAS, Maria Fernanda Condes. Insulin action/signaling in amygdala of controls and obeses animals : effects on food intake, inflammation and ER stress = Regulação da ação e sinalização de insulina em amígdala de animais controles e obesos : efeitos na ingestão alimentar, via inflamatória e stress de retículo endoplasmático. 2012. Tese (Doutorado) – Faculdade de Ciências Médicas. Universidade Estadual de Campinas (UNICAMP). (11/17673-2)

BERGONSI, Paula Gabriele Fernandes Quaresma. Proteína CLK2 (Cdc-2-like kinase 2) no hipotálamo é importante para a manutenção da homeostase energética. 2017. Tese (Doutorado) – Universidade Estadual de Campinas, Faculdade de Ciências Médicas. (12/10058-3)

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