CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Cláudio Marinho is a Full Professor in the Department of Parasitology at the Institute of Biomedical Sciences of USP (ICB-USP). A biologist with master's and doctoral degrees in Immunology from USP, he completed postdoctoral studies at the Gulbenkian Institute of Science (Portugal) and obtained the title of Associate Professor in 2018. His scientific output includes more than 100 articles in international journals, focusing on the immunopathological mechanisms of malaria, especially during pregnancy. He has been an editor of PLOS ONE since 2009 and a reviewer for more than 20 journals, including Malaria Journal, Infection and Immunity, Scientific Reports, and The Lancet Infectious Diseases. He serves as an ad hoc consultant to national and international agencies, including FAPESP, CNPq, CAPES, Fiocruz, FAPEAM, FAPEMA, FAPEB, and MRC (United Kingdom). He has supervised and mentored more than 40 researchers at the master's, doctoral, and postdoctoral levels. He held management positions at ICB, including chairing the Research and Innovation Committee, the Faculty Committee, the Central Animal Facility Committee, and the Office of Good Scientific Practices, and was head and deputy head of the Department of Parasitology for 8 years. Currently, he is the representative of the ICB Congregation to the University Council of USP. (Source: Lattes Curriculum)
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Malaria remains a significant global health issue, with millions of cases and hundreds of thousands of deaths annually, predominantly caused by Plasmodium falciparum (Pf) and Plasmodium vivax (Pv). Control efforts are complicated by emerging drug resistance, particularly against artemisinin-based treatments (ACTs). While artemisinin resistance is primarily observed in Southeast Asia, the …
# Background:Each year, 92 million pregnant women are at risk of contracting malaria during pregnancy, with the underestimation of the mortality and morbidity burden associated with Plasmodium vivax. During pregnancy, P. vivax infection is associated with low birth weight, maternal anaemia, premature delivery, and stillbirth. In the State of Acre (Brazil), high transmission leaves pregnan…
The increase in cardiovascular disease in developing countries seems to occur in the setting of high incedence infectious diseases. Malaria is a highly prevalent infectious disease in these regions, with 230 million cases per year. There are some studies suggesting that malaria causes structural changes in the heart and affects specific vascular pathways, leading to an increased risk of h…
Malaria in pregnancy is characterized by the presence of Plasmodium spp. in the peripheral blood or placenta, being one of the main causes of mortality in tropical regions, which causes maternal anemia, abortion, intrauterine growth restriction, preterm delivery and low birth weight. Plasmodium (P.) vivax is the dominant malaria species outside the African continent, accounting for about …
(Only some records are available in English at this moment)
Malaria caused by Plasmodium vivax remains a significant global public health challenge, especially in endemic regions of Latin America and Southeast Asia. Despite advances in disease control programs, the development of effective vaccines against P. vivax has been limited by the high antigenic variability of epitopes expressed throughout the different stages of the parasite's life cycle.…
Malaria during pregnancy is very important from an epidemiological perspective, as both the mother and fetus are at risk for the disease. Physiological and immunological changes can compromise maternal- fetal exchanges, leading to placental dysfunction and complications such as anaemia, low birth weight, intrauterine growth restriction, and premature birth. Polymorphisms in genes encoding…
Malaria remains the most important parasitic disease worldwide due to its high morbidity and mortality and its wide geographical distribution in tropical regions. In Brazil, this disease is mainly caused by Plasmodium vivax species and more than 99% of cases occur in the Legal Amazon region. Genetic components of the parasite and the host can influence the infection course, such as the pr…
(Only some records are available in English at this moment)
Malaria represents a public health problem in most tropical countries, with high incidence and mortality rates,and with pregnant women being a risk group for the disease. During pregnancy, infection with Plasmodium falciparum induce the increase of prematurity and maternal and fetal mortality, in addition to intrauterine growth restriction, which leads to low birth weight.In this context,…
An increase in cardiovascular diseases recorded in developing countries appears to occur simultaneously with an increase in the burden of infectious diseases. In this sense, Malaria is a highly prevalent infectious disease in these places, where approximately 230 million cases are recorded per year. There are some studies and case reports that suggest that Malaria causes structural change…
Malaria in pregnancy is characterized as the presence of Plasmodium spp. in the peripheral blood or placenta, being one of the main causes of mortality in tropical regions, causing maternal Anemia, abortion, intrauterine growth restriction, preterm delivery and low birth weight. Placental Malaria is one of the serious consequences of Malaria in pregnancy, occurring in about 20% to 50% of …
(Only some records are available in English at this moment)
Malaria still represents a burden worldwide and pregnant women are at risk of developing placental malaria, a complication of Plasmodium falciparum infections with sequestration of infected red blood cells in the placenta intervillous space. This complication is associated with placental insufficiency, which leads to adverse outcomes, such as stillbirth, low birth weight, prematurity, and…
Malaria in pregnancy is a serious public health problem, with placental malaria being one of its serious consequences and one of the main causes of adverse pregnancy outcomes. Despite many studies, it remains unclear which peripheral blood infections during pregnancy lead to development of placental malaria. Whereas it is clear that placental parasites present a distinct phenotype from th…
Malaria in pregnancy is a serious public health problem and is characterized by the presence of Plasmodium spp. in the peripheral blood or the placenta, impacting on maternal and foetal health. Although P. vivax burden in pregnancy is less described than P. falciparum, recent studies indicate that both species represent a threaten to mother and foetus. Nevertheless, several hypotheses hav…