CV Lattes
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Universidade de São Paulo (USP). Instituto de Química de São Carlos (IQSC) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Química from Universidade de São Paulo (1986), master's at Química Analítica São Carlos from Universidade de São Paulo (1990) and doctorate at Ciências from Northeastern University Graduate School Of Arts And Sciences (1997). He is currently full professor at Universidade de São Paulo. Has experience in Chemistry, acting on the following subjects: ce, instrumentação, análises genéticas, seqüênciamento de dna and microchip. (Source: Lattes Curriculum)
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The miniaturization of sensors and their integration into electronic equipment is essential for robotics, Internet of Things, and artificial intelligence applications. Direct application to the human body, animals, plants, packaging, requires flexible and/or wearable sensors, preferably obtained with low-cost and easily scalable techniques. In this Project, sensors with flexible structure…
The Amazon rainforest has an invaluable wealth of fauna and flora. However, the vertiginous deforestation of the last ten years threatens this natural heritage of humanity. Logging, livestock, mining, and soy planting are the protagonists of deforestation. Although soy dominates the field of plant-based products (plant-based), an alternative protein source to animal protein, the search fo…
Rare earth ions doped upconverting nanoparticles (UCNPs) are luminescent nanomaterials with the ability to convert low energy (infrared) photons into visible and ultraviolet radiation through energy transfer, cooperative and excited state absorption mechanisms. The IR excitation can be done with low-cost diode lasers and provides great advantage to the use of UCNPs in biological applicati…
The IQSC presents its proposal to invest the amount of R$ 582.733,79, related to the 2021 FAPESP institutional infrastructure costs in the acquisition of liquid nitrogen and special gases, chemical waste disposal, maintenance of research equipment, equipments acquisition of research laboratories and laboratory adjustments. (AU)
The IQSC presents its proposal to invest the amount of R$ 260.964,05, related to the FAPESP institutional infrastructure costs of 2020 in the acquisition of liquid nitrogen and special gases, chemical waste disposal, maintenance of research equipment, equipments acquisition of research laboratories and permanent and consumption material for the improvement of research laboratories compute…
(Only some records are available in English at this moment)
The process of new drug discovery is complex and faces significant challenges, such as a high failure rate and limitations in preclinical steps through the use of conventional methods such as 2D cell culture and animal testing. Although they play an important role in basic research, both formats have several limitations, especially the mimicry of human physiology. To overcome these limita…
Currently, pancreatic cancer is an invasive cancer that is difficult to treat, and the success of clinical trials against cancer remains low. Pancreatic ductal adenocarcinoma is the most common, and the 5-year survival rate is less than 10%. Traditional in vitro tumor models do not replicate the complexity of the tumor microenvironment and response to therapies, so this project aims to de…
The miniaturization of sensors and their integration into electronic equipment is essential for robotics, Internet of Things, and artificial intelligence applications. Direct application to the human body, animals, plants, packaging, requires flexible and/or wearable sensors, preferably obtained with low-cost and easily scalable techniques. In this Project, sensors with flexible structure…
(Only some records are available in English at this moment)
Melatonin, a hormone known for its function in the regulation of the circadian cycle, is also responsible for many other aspects that surround human health, such as the immune system's functioning. In the current context, the detection and quantification of melatonin is a challenge, requiring specialized apparatus (radioimmunoassays, ELISA (Enzyme-Linked Immuno Sorbent Assay), among other…
The real-time quantitative PCR (qPCR) methodology has become, in recent years, the reference diagnostic technology for various infections, including the current COVID-19 pandemic. However, dependence on specialized equipment and highly trained personnel restrict this method to centralized laboratories. Alternative methods of amplifying and detecting nucleic acids, based on isothermal ampl…
(Only some records are available in English at this moment)
The stress experienced by pregnant women is related to several health problems for the moms and babies, such as prematurity, low birth weight, and adverse effects on long-term child development. Maternal stress outcomes in increased fetal heart rate and decreased fetal movement. Cortisol is known as "stress hormone", and deviations from normal levels is associated with such condition. The…
Currently, the analytical performance to characterize all complexity of a proteome is not sufficient. This complexity has been the main subject of study at Yates Lab for the last 25 years with significant scientific impact on the evolution of the field. With this in mind, we propose a series of studies to try to improve analytical strategies to proteomics, such as i) new chemometrics stra…
Cancer cells have specific receptors with high affinity to folate and are highly replicative. Alpha folate receptor (FR-±) are extracellular proteins with specific biochemical properties, since with rare exceptions, it is induced selectively in cancerous tissues and rarely expressed in normal cells, being highly sensitive and specific. Aiming disease detection, our group reported the use …
| 2 / 2 | Ongoing grants |
| 17 / 14 | Completed research grants |
| 6 / 6 | Ongoing scholarships in Brazil |
| 36 / 20 | Completed scholarships in Brazil |
| 4 / 3 | Completed scholarships abroad |
| 65 / 45 | All research grants and scholarships |
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